The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature. (Q33807381)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature.	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Delphine Fradin

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Danielle Gutman

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

15

object named as

Nir Barzilai

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

3

object named as

Temuri Budagov

1 reference

Europe PubMed Central

23 March 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

Danny Ben-Avraham

1

object named as

Danny Ben-Avraham

1 reference

Europe PubMed Central

23 March 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

author name string

Diddahally R Govindaraju

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Peter Durda

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Bing Liu

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Sandy Ott

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Robert Kaplan

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Alex Reiner

12

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Alan R Shuldiner

13

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Pinchas Cohen

14

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Gil Atzmon

16

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Pierre Bougnères

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

publication date

16 June 2017

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Science Advances

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

e1602025

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Lower circulating insulin-like growth factor-I is associated with better cognition in females with exceptional longevity without compromise to muscle mass and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Growth hormone secretion is diminished and tightly controlled in humans enriched for familial longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Healthspan and longevity can be extended by suppression of growth hormone signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Height-reducing variants and selection for short stature in Sardinia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Exon 3-deleted and full-length growth hormone receptor polymorphism frequencies in an Iranian population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Genetic and Epigenetic Modulation of Growth Hormone Sensitivity Studied With the IGF-1 Generation Test

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Growth hormone replacement in adults - current standards and new perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Influence of growth hormone receptor (GHR) exon 3 and -202A/C IGFBP-3 genetic polymorphisms on clinical and biochemical features and therapeutic outcome of patients with acromegaly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

The Regulation of IGF-1 Gene Transcription and Splicing during Development and Aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Human Ageing Genomic Resources: integrated databases and tools for the biology and genetics of ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Growth hormone receptor (GHR) exon 3 polymorphism status detection by dual-enzyme-linked immunosorbent assay (ELISA).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Growth hormone receptor polymorphism and growth hormone therapy response in children: a Bayesian meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Increasing circulating IGFBP1 levels improves insulin sensitivity, promotes nitric oxide production, lowers blood pressure, and protects against atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Pleiotropic effects of growth hormone signaling in aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

The growth hormone receptor: mechanism of activation and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Impact of the exon 3-deleted growth hormone (GH) receptor polymorphism on baseline height and the growth response to recombinant human GH therapy in GH-deficient (GHD) and non-GHD children with short stature: a systematic review and meta-analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Functionally significant insulin-like growth factor I receptor mutations in centenarians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Lipoprotein genotype and conserved pathway for exceptional longevity in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Growth hormone (GH) pharmacogenetics: influence of GH receptor exon 3 retention or deletion on first-year growth response and final height in patients with severe GH deficiency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Control of aging and longevity by IGF-I signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

The paradox of the insulin/IGF-1 signaling pathway in longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Clinical phenotype of families with longevity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Unique lipoprotein phenotype and genotype associated with exceptional longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Heterozygous nonsense mutation in exon 3 of the growth hormone receptor (GHR) in severe GH insensitivity (Laron syndrome) and the issue of the origin and function of the GHRd3 isoform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Evolutionary medicine: from dwarf model systems to healthy centenarians?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

PedCheck: a program for identification of genotype incompatibilities in linkage analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Characterization of the human growth hormone receptor gene and demonstration of a partial gene deletion in two patients with Laron-type dwarfism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

The Cardiovascular Health Study: design and rationale

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

4 July 2018

Reduced longevity in untreated patients with isolated growth hormone deficiency.

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

Species-specific alternative splice mimicry at the growth hormone receptor locus revealed by the lineage of retroelements during primate evolution.

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

A common polymorphism of the growth hormone receptor is associated with increased responsiveness to growth hormone.

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

The d3-growth hormone (GH) receptor polymorphism is associated with increased responsiveness to GH in Turner syndrome and short small-for-gestational-age children.

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

RhoA, Rho kinase, JAK2, and STAT3 may be the intracellular determinants of longevity implicated in the progeric influence of obesity: Insulin, IGF-1, and leptin may all conspire to promote stem cell exhaustion.

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

Can Growth Hormone (GH) Accelerate Aging? Evidence from GH-Transgenic Mice

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

Influence of the d3GH receptor polymorphism on the metabolic and biochemical phenotype of GH-deficient adults at baseline and during short- and long-term recombinant human GH replacement therapy

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

The GH receptor exon 3 deleted/full-length polymorphism is associated with central adiposity in the general population

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

Disruption of the GH Receptor Gene in Adult Mice Increases Maximal Lifespan in Females.

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

Antagonistic pleiotropy and the stress theory of aging.

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

Plasma HDL levels highly correlate with cognitive function in exceptional longevity

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

Abnormality of gait as a predictor of non-Alzheimer's dementia.

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

Exon 3-Deleted/Full-Length Growth Hormone Receptor Polymorphism Genotype Frequencies in Spanish Short Small-for-Gestational-Age (SGA) Children and Adolescents (n = 247) and in an Adult Control Population (n = 289) Show Increasedfl/flin Short SGA

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

GHR exon 3 polymorphism: Association with type 2 diabetes mellitus and metabolic disorder

1 reference

https://api.crossref.org/works/10.1126%2FSCIADV.1602025

21 January 2018

Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473676

30 October 2018

Aging and longevity: the IGF-1 enigma

1 reference

https://pubmed.ncbi.nlm.nih.gov/28630896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The exon-3 deletion of the growth hormone receptor (GHR) gene still has a limited impact in clinical endocrinology

1 reference

https://pubmed.ncbi.nlm.nih.gov/28630896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRCA 1 and 2--A Genetic Link to Familial Breast and Ovarian Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28630896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A polymorphism in the growth hormone receptor is associated with height in children with Prader-Willi syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/28630896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

1 reference

https://pubmed.ncbi.nlm.nih.gov/28630896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1126/SCIADV.1602025

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28630896%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33807381&oldid=2119333588"