CRIPTO1 expression in EGFR-mutant NSCLC elicits intrinsic EGFR-inhibitor resistance. (Q33808203)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24911146%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

CRIPTO1 expression in EGFR-mutant NSCLC elicits intrinsic EGFR-inhibitor resistance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24911146%20AND%20SRC:MED&resulttype=core&format=json

non-small-cell lung carcinoma

20 March 2020

main subject

1 reference

8

1 reference

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20 March 2020

Yasushi Yatabe

9

1 reference

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20 March 2020

Tony Mok

12

1 reference

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20 March 2020

Giuseppe Giaccone

17

1 reference

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20 March 2020

author name string

Kang-Seo Park

1

1 reference

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20 March 2020

Mark Raffeld

2

1 reference

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20 March 2020

Yong Wha Moon

3

1 reference

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20 March 2020

Liqiang Xi

4

1 reference

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20 March 2020

Caterina Bianco

5

1 reference

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20 March 2020

Trung Pham

6

1 reference

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20 March 2020

Liam C Lee

7

1 reference

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20 March 2020

Isamu Okamoto

10

1 reference

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20 March 2020

Deepa Subramaniam

11

1 reference

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20 March 2020

Ji Luo

14

1 reference

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20 March 2020

David S Salomon

15

1 reference

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20 March 2020

Yisong Wang

16

1 reference

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20 March 2020

Rafael Rosell

13

1 reference

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20 March 2020

language of work or name

English

0 references

publication date

9 June 2014

1 reference

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Journal of Clinical Investigation

20 March 2020

published in

1 reference

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20 March 2020

volume

124

1 reference

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20 March 2020

issue

7

1 reference

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20 March 2020

page(s)

3003-3015

1 reference

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EGFR-TKI resistance due to BIM polymorphism can be circumvented in combination with HDAC inhibition.

20 March 2020

cites work

1 reference

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Nodal promotes invasive phenotypes via a mitogen-activated protein kinase-dependent pathway

4 July 2018

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Nodal signalling in embryogenesis and tumourigenesis.

4 July 2018

1 reference

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c-Src activation mediates erlotinib resistance in head and neck cancer by stimulating c-Met

4 July 2018

1 reference

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Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer

4 July 2018

1 reference

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Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers

4 July 2018

1 reference

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A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer

4 July 2018

1 reference

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ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cells

4 July 2018

1 reference

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BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors.

4 July 2018

1 reference

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Expression and functional role of CRIPTO-1 in cutaneous melanoma

4 July 2018

1 reference

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Src/FAK-mediated regulation of E-cadherin as a mechanism for controlling collective cell movement: insights from in vivo imaging

4 July 2018

1 reference

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Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

4 July 2018

1 reference

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EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells

4 July 2018

1 reference

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MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer

4 July 2018

1 reference

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Targeting the embryonic gene Cripto-1 in cancer and beyond

4 July 2018

1 reference

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Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

De novo resistance to epidermal growth factor receptor-tyrosine kinase inhibitors in EGFR mutation-positive patients with non-small cell lung cancer

4 July 2018

1 reference

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TDGF1 is a novel predictive marker for metachronous metastasis of colorectal cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

SRC promotes survival and invasion of lung cancers with epidermal growth factor receptor abnormalities and is a potential candidate for molecular-targeted therapy.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Diagnostic assay based on hsa-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

CRIPTO3, a presumed pseudogene, is expressed in cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Epithelial to mesenchymal transition derived from repeated exposure to gefitinib determines the sensitivity to EGFR inhibitors in A549, a non-small cell lung cancer cell line

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Concurrent chemoradiotherapy with cisplatin and vinorelbine for stage III non-small cell lung cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

MicroRNAs in disease and potential therapeutic applications

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Anti-Cripto Mab inhibit tumour growth and overcome MDR in a human leukaemia MDR cell line by inhibition of Akt and activation of JNK/SAPK and bad death pathways

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer

4 July 2018

1 reference

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Update on epidermal growth factor receptor mutations in non-small cell lung cancer

4 July 2018

1 reference

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Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis

4 July 2018

1 reference

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Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer

4 July 2018

1 reference

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Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations

4 July 2018

1 reference

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Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines.

4 July 2018

1 reference

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Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition

4 July 2018

1 reference

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Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Cripto-1: an oncofetal gene with many faces

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib

4 July 2018

1 reference

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Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Epithelial mesenchymal transition is a characteristic of hyperplasias and tumors in mammary gland from MMTV-Cripto-1 transgenic mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Combination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myeloma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Cripto: a novel target for antibody-based cancer immunotherapy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Cripto-1 overexpression leads to enhanced invasiveness and resistance to anoikis in human MCF-7 breast cancer cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

A Nodal- and ALK4-independent signaling pathway activated by Cripto-1 through Glypican-1 and c-Src

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Cripto-1 activates nodal- and ALK4-dependent and -independent signaling pathways in mammary epithelial Cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Differential immunohistochemical detection of transforming growth factor alpha, amphiregulin and CRIPTO in human normal and malignant breast tissues

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Differential immunohistochemical detection of amphiregulin and cripto in human normal colon and colorectal tumors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

The impact of EGFR T790M mutations and BIM mRNA expression on outcome in patients with EGFR-mutant NSCLC treated with erlotinib or chemotherapy in the randomized phase III EURTAC trial

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Primary resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with non-small-cell lung cancer harboring TKI-sensitive EGFR mutations: an exploratory study

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Role of Src family kinases in acquired resistance to EGFR therapies in cancer

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Positive association of up-regulated Cripto-1 and down-regulated E-cadherin with tumour progression and poor prognosis in gastric cancer

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4071378

Taxol in the treatment of lung cancer

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24911146

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overexpression of Cripto and its prognostic significance in breast cancer: a study with long-term survival

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24911146

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI73048

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24911146%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24911146%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

24911146

1 reference