Hypoxia potentiates glioma-mediated immunosuppression (Q33809268)

29 July 2017

Hypoxia potentiates glioma-mediated immunosuppression (English)

1 reference

29 July 2017

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1 reference

Gregory Fuller

5

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author name string

Jun Wei

1

1 reference

29 July 2017

Adam Wu

2

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29 July 2017

Ling-Yuan Kong

3

1 reference

29 July 2017

Yongtao Wang

4

1 reference

29 July 2017

Isabella Fokt

6

1 reference

29 July 2017

Giovanni Melillo

7

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29 July 2017

Waldemar Priebe

8

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29 July 2017

Amy B Heimberger

9

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29 July 2017

language of work or name

English

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publication date

20 January 2011

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29 July 2017

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29 July 2017

6

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29 July 2017

1

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29 July 2017

e16195

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Creative Commons Attribution 4.0 International

29 July 2017

start time

20 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Glioma-associated cancer-initiating cells induce immunosuppression

4 July 2018

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4 July 2018

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Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1 alpha transcription factor.

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4 July 2018

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4 July 2018

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A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells

4 July 2018

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Tumor-associated galectin-3 modulates the function of tumor-reactive T cells

4 July 2018

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Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF.

4 July 2018

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Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy

4 July 2018

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Hypoxia-inducible factors, stem cells, and cancer

4 July 2018

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Altered macrophage differentiation and immune dysfunction in tumor development

4 July 2018

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Vascular endothelial growth factor and immunosuppression in cancer: current knowledge and potential for new therapy.

4 July 2018

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Macrophages regulate the angiogenic switch in a mouse model of breast cancer

4 July 2018

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

4 July 2018

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A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo

4 July 2018

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Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12.

4 July 2018

1 reference

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Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway

4 July 2018

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The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses

4 July 2018

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Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

4 July 2018

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4 July 2018

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STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells

4 July 2018

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HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.

4 July 2018

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Impact of Tumor-Derived CCL2 on Macrophage Effector Function

4 July 2018

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CSF-1 regulation of the wandering macrophage: complexity in action

4 July 2018

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4 July 2018

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Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues.

4 July 2018

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Physiological control of immune response and inflammatory tissue damage by hypoxia-inducible factors and adenosine A2A receptors.

4 July 2018

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Tumour-educated macrophages promote tumour progression and metastasis

4 July 2018

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4 July 2018

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Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

4 July 2018

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Expression pattern of galectin-3 in neural tumor cell lines

4 July 2018

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Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast

4 July 2018

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Tumor-induced immune dysfunction: the macrophage connection.

4 July 2018

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

4 July 2018

1 reference

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IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways

4 July 2018

1 reference

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Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024401

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

4 July 2018

1 reference

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The origin and function of tumor-associated macrophages

4 July 2018

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Neurospheres enriched in cancer stem-like cells are highly effective in eliciting a dendritic cell-mediated immune response against malignant gliomas.

4 July 2018

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Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha

21 January 2018

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Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha.

21 January 2018

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A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients.

21 January 2018

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T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response

21 January 2018

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Hypoxia causes an increase in phagocytosis by macrophages in a HIF-1alpha-dependent manner.

21 January 2018

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ICER/CREM-mediated transcriptional attenuation of IL-2 and its role in suppression by regulatory T cells

21 January 2018

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WP744, a novel anthracycline with enhanced proapoptotic and antileukemic activity

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21283755

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of HIF-1, galectin-3, cox-2 and Wilms tumor-1 protein in multiple schwannomas of the conus medullaris

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21283755

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TGF-beta enhances macrophage ability to produce IL-10 in normal and tumor-bearing mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21283755

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0016195

1 reference

29 July 2017

0 references

1 reference

29 July 2017

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