PTEN mutations as a cause of constitutive insulin sensitivity and obesity. (Q33811688)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22970944%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

PTEN mutations as a cause of constitutive insulin sensitivity and obesity (English)

1 reference

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13 February 2020

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1 reference

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13 February 2020

Katherine L Lachlan

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13 February 2020

Jonathan Cummings Levy

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13 February 2020

Michael Wakelam

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13 February 2020

Fredrik Karpe

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13 February 2020

Anna Gloyn

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13 February 2020

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Qifeng Zhang

1 reference

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13 February 2020

author name string

Aparna Pal

1

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13 February 2020

Thomas M Barber

2

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13 February 2020

Simon A Rudge

4

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13 February 2020

Nicola S Cooper

7

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13 February 2020

Helen Linden

8

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13 February 2020

Lisa Walker

11

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13 February 2020

language of work or name

English

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publication date

1 September 2012

1 reference

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The New England Journal of Medicine

13 February 2020

published in

1 reference

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13 February 2020

volume

367

1 reference

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13 February 2020

issue

11

1 reference

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13 February 2020

page(s)

1002-1011

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Systemic elevation of PTEN induces a tumor-suppressive metabolic state

13 February 2020

cites work

1 reference

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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

28 July 2018

1 reference

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Cancer as an endocrine problem

28 July 2018

1 reference

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Evaluation of a variant in the transcription factor 7-like 2 (TCF7L2) gene and prostate cancer risk in a population-based study

28 July 2018

1 reference

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Multiple loci identified in a genome-wide association study of prostate cancer

28 July 2018

1 reference

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The twentieth century struggle to decipher insulin signalling

28 July 2018

1 reference

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Adiponectin: a link between obesity and cancer

28 July 2018

1 reference

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Essential role of Pten in body size determination and pancreatic beta-cell homeostasis in vivo

28 July 2018

1 reference

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Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes

28 July 2018

1 reference

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Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study

28 July 2018

1 reference

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Adipose tissue function in the insulin-resistance syndrome

28 July 2018

1 reference

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The metabolic syndrome--a new worldwide definition

28 July 2018

1 reference

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Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissue

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072504

Muscle-specific Pten deletion protects against insulin resistance and diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072504

Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072504

PTEN: tumour suppressor, multifunctional growth regulator and more

28 July 2018

1 reference

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Correct homeostasis model assessment (HOMA) evaluation uses the computer program

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072504

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072504

Autosomal dominant macrocephaly: benign familial macrocephaly or a new syndrome?

28 July 2018

1 reference

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Glucose clamp technique: a method for quantifying insulin secretion and resistance

28 July 2018

1 reference

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A continuum model for tumour suppression

28 July 2018

1 reference

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Insulin-sensitive obesity

30 October 2018

1 reference

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PTEN hamartoma tumor syndromes.

30 October 2018

1 reference

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Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity

30 October 2018

1 reference

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Elevated plasma adiponectin in humans with genetically defective insulin receptors.

30 October 2018

1 reference

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Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072504

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

30 October 2018

1 reference

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Understanding oral glucose tolerance: comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072504

Two variants on chromosome 17 confer prostate cancer risk and the one in TCF2 protects against type 2 diabetes

30 October 2018

1 reference

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Cancer and diabetes: are we ready for prime time?

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22970944

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Accelerated decline of blood glucose after intravenous glucose injection in a patient with Cowden disease having a heterozygous germline mutation of the PTEN/MMAC1 gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22970944

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1056/NEJMOA1113966

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22970944%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22970944%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

22970944

1 reference