The role of cyclooxygenases in inflammation, cancer, and development (Q33814331)

29 July 2017

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title

The role of cyclooxygenases in inflammation, cancer, and development (English)

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29 July 2017

Williams CS

1

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29 July 2017

Mann M

series ordinal

2

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29 July 2017

DuBois RN

series ordinal

3

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29 July 2017

language of work or name

English

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publication date

1 December 1999

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29 July 2017

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29 July 2017

18

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29 July 2017

7908-7916

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29 July 2017

55

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203286

29 July 2017

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cites work

Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Platelet-activating factor and retinoic acid synergistically activate the inducible prostaglandin synthase gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

The catalytic outcomes of the constitutive and the mitogen inducible isoforms of prostaglandin H2 synthase are markedly affected by glutathione and glutathione peroxidase(s)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Developmental expression of the cyclo-oxygenase-1 and cyclo-oxygenase-2 genes in the peri-implantation mouse uterus and their differential regulation by the blastocyst and ovarian steroids.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Regulation of mesangial cell cyclooxygenase synthesis by cytokines and glucocorticoids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isozymes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-alpha and phorbol ester

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Risk for Serious Gastrointestinal Complications Related to Use of Nonsteroidal Anti-inflammatory Drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Inducible cyclooxygenase may have anti-inflammatory properties

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Meloxicam inhibits the growth of colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Phorbol ester and epidermal growth factor enhance the expression of two inducible prostaglandin H synthase genes in rat tracheal epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Alteration of tumor growth by aspirin and indomethacin: studies with two transplantable tumors in mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Prostaglandin endoperoxide-H synthase-1 and -2 messenger ribonucleic acid levels in human amnion with spontaneous labor onset

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Cyclooxygenase 2 is up-regulated and localized to macrophages in the intestine of Min mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Aspirin-like molecules that covalently inactivate cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Characterization of Prostaglandin G/H Synthase 1 and 2 in rat, dog, monkey, and human gastrointestinal tracts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

ONCOGENESIS: Landscaping the Cancer Terrain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Sulindac causes regression of rectal polyps in familial adenomatous polyposis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Cancer statistics, 1998.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Multiple female reproductive failures in cyclooxygenase 2-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Protective effects of prostaglandins against gastric mucosal damage: current knowledge and proposed mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Lipopolysaccharide induces prostaglandin H synthase-2 in alveolar macrophages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Prostaglandin E2 levels and lymphocyte subsets in portal venous drainage of colorectal cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Use of azoxymethane-induced foci of aberrant crypts in rat colon to identify potential cancer chemopreventive agents.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Effect of indomethacin on intestinal tumors induced in rats by the acetate derivative of dimethylnitrosamine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Transient expression of prostaglandin endoperoxide synthase-2 during mouse macrophage activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Distinct roles of prostaglandin H synthases 1 and 2 in T-cell development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Effects of nonsteroidal antiinflammatory drugs on platelet function and systemic hemostasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastro-intestinal ulcer models in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Coordinate regulation of cyclooxygenase-2 and TGF-beta1 in replication error-positive colon cancer and azoxymethane-induced rat colonic tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Differential expression of matrilysin and cyclooxygenase-2 in intestinal and colorectal neoplasms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Identification of a phorbol ester-repressible v-src-inducible gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Nonsteroidal anti-inflammatory drugs and peptic ulcer disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Aspirin use and reduced risk of fatal colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Comparison of recombinant cyclooxygenase-2 to native isoforms: aspirin labeling of the active site.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Sulindac sulfide, but not sulindac sulfone, inhibits colorectal cancer growth.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Elevated cyclooxygenase-2 levels in Min mouse adenomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Analysis of hydroperoxide-induced tyrosyl radicals and lipoxygenase activity in aspirin-treated human prostaglandin H synthase-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Sulindac inhibits activation of the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203286

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203286

1 reference

Dimensions Publication ID

29 July 2017

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1 reference