Requirement of phospholipase D1 activity in H-RasV12-induced transformation (Q33817312)

29 July 2017

title

Requirement of phospholipase D1 activity in H-RasV12-induced transformation (English)

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29 July 2017

F Gregory Buchanan

1

1 reference

29 July 2017

Matt McReynolds

2

1 reference

29 July 2017

Anthony Couvillon

3

1 reference

29 July 2017

Yoonseok Kam

4

1 reference

29 July 2017

Vijaykumar R Holla

5

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29 July 2017

Raymond N Dubois

6

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29 July 2017

John H Exton

7

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29 July 2017

language of work or name

English

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publication date

24 January 2005

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

102

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29 July 2017

issue

5

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29 July 2017

page(s)

1638-1642

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The P34G mutation reduces the transforming activity of K-Ras and N-Ras in NIH 3T3 cells but not of H-Ras.

29 July 2017

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Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid

28 July 2018

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Roles of phosphatidylinositol 3'-kinase and mammalian target of rapamycin/p70 ribosomal protein S6 kinase in K-Ras-mediated transformation of intestinal epithelial cells

28 July 2018

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Transmodulation between Phospholipase D and c-Src Enhances Cell Proliferation

28 July 2018

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Elevated phospholipase D activity in H-Ras- but not K-Ras-transformed cells by the synergistic action of RalA and ARF6

28 July 2018

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The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade

28 July 2018

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Transformation of cells overexpressing a tyrosine kinase by phospholipase D1 and D2.

28 July 2018

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Phosphatidic acid-mediated mitogenic activation of mTOR signaling

28 July 2018

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Inhibition of ChoK is an efficient antitumor strategy for Harvey-, Kirsten-, and N-ras-transformed cells.

28 July 2018

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Phospholipase D activity is required for actin stress fiber formation in fibroblasts

28 July 2018

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28 July 2018

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Differential roles of Akt, Rac, and Ral in R-Ras-mediated cellular transformation, adhesion, and survival

28 July 2018

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Regulation of phospholipase D.

28 July 2018

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Involvement of tyrosine phosphorylation and protein kinase C in the activation of phospholipase D by H2O2 in Swiss 3T3 fibroblasts

28 July 2018

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

28 July 2018

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28 July 2018

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Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

28 July 2018

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Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha

28 July 2018

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Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation

28 July 2018

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Biological assays for Ras transformation

28 July 2018

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Evidence that v-Src-induced phospholipase D activity is mediated by a G protein

28 July 2018

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28 July 2018

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Ras mediates the activation of phospholipase D by v-Src

28 July 2018

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Involvement of Ral GTPase in v-Src-induced phospholipase D activation

28 July 2018

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28 July 2018

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Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

28 July 2018

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A genetic model for colorectal tumorigenesis

28 July 2018

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v-Src increases diacylglycerol levels via a type D phospholipase-mediated hydrolysis of phosphatidylcholine

28 July 2018

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28 July 2018

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Increasing complexity of Ras signaling.

21 January 2018

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Phospholipase D and its product, phosphatidic acid, mediate agonist-dependent raf-1 translocation to the plasma membrane and the activation of the mitogen-activated protein kinase pathway

21 January 2018

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H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis

21 January 2018

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Phospholipase D confers rapamycin resistance in human breast cancer cells

21 January 2018

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Phospholipase D2 stimulates cell protrusion in v-Src-transformed cells

21 January 2018

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Increased Activity and Expression of Phospholipase D2 in Human Colorectal Cancer

21 January 2018

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Phospholipase D in cell proliferation and cancer

30 October 2018

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Roles of phospholipase D in apoptosis and pro-survival

30 October 2018

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30 October 2018

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Phospholipase D activity in human gastric carcinoma

21 January 2018

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12 December 2020

Overexpression of phospholipase D1 in human breast cancer tissues

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12 December 2020

Increased activity and intranuclear expression of phospholipase D2 in human renal cancer

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12 December 2020

Conserved amino acids at the C-terminus of rat phospholipase D1 are essential for enzymatic activity

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12 December 2020

Protein kinase C isoforms involved in the transcriptional activation of cyclin D1 by transforming Ha-Ras

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0406698102

1 reference

29 July 2017

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29 July 2017

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