Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation (Q33819040)

29 July 2017

Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation (English)

1 reference

29 July 2017

1 reference

1

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2 June 2020

Alexander V. Misharin

2

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2 June 2020

Jack Hutcheson

6

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2 June 2020

author name string

Angelica K Gierut

3

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2 June 2020

Rana Saber

4

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2 June 2020

G Kenneth Haines

5

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2 June 2020

Stephen M Hedrick

7

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2 June 2020

Chandra Mohan

8

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2 June 2020

G Scott Budinger

9

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2 June 2020

Christian Stehlik

10

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2 June 2020

Harris Perlman

11

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2 June 2020

language of work or name

English

0 references

publication date

7 May 2014

1 reference

29 July 2017

Journal of Immunology

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2 June 2020

volume

192

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2 June 2020

issue

12

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2 June 2020

page(s)

5548-5560

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Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway

2 June 2020

cites work

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FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.

4 July 2018

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Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammation

4 July 2018

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4 July 2018

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Signals via the adaptor MyD88 in B cells and DCs make distinct and synergistic contributions to immune activation and tissue damage in lupus

4 July 2018

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Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

4 July 2018

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Myeloid dendritic cells from B6.NZM Sle1/Sle2/Sle3 lupus-prone mice express an IFN signature that precedes disease onset

4 July 2018

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Distinct roles of myeloid and plasmacytoid dendritic cells in systemic lupus erythematosus.

4 July 2018

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TLR7 and TLR9 in SLE: when sensing self goes wrong

4 July 2018

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A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment.

4 July 2018

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Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways

4 July 2018

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Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice

4 July 2018

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Animal models of molecular pathology systemic lupus erythematosus

4 July 2018

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Microbiota and autoimmune disease: the hosted self

4 July 2018

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It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival

4 July 2018

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Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation

4 July 2018

1 reference

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cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

4 July 2018

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RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein

4 July 2018

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Mechanisms of necroptosis in T cells

4 July 2018

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

4 July 2018

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RIP3 mediates the embryonic lethality of caspase-8-deficient mice

4 July 2018

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Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage

4 July 2018

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Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus

4 July 2018

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Dendritic cell function in lupus: Independent contributors or victims of aberrant immune regulation

4 July 2018

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Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

4 July 2018

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BH3-only proteins in rheumatoid arthritis: potential targets for therapeutic intervention.

4 July 2018

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The many roles of FAS receptor signaling in the immune system

4 July 2018

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The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages

4 July 2018

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Inflammatory signals in dendritic cell activation and the induction of adaptive immunity

4 July 2018

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Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis

4 July 2018

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The innate immune system in SLE: type I interferons and dendritic cells

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis

4 July 2018

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Activation of NF-kappaB by FADD, Casper, and caspase-8.

4 July 2018

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4 July 2018

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4 July 2018

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Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome.

4 July 2018

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Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

30 October 2018

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IRF-3 and Bax: a deadly affair

30 October 2018

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30 October 2018

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Fas ligation induces IL-1beta-dependent maturation and IL-1beta-independent survival of dendritic cells: different roles of ERK and NF-kappaB signaling pathways.

30 October 2018

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Monocyte-derived dendritic cells over-express CD86 in patients with systemic lupus erythematosus

30 October 2018

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12 December 2020

Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage

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12 December 2020

Dendritic cell apoptosis in the maintenance of immune tolerance

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12 December 2020

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Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity

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Identifiers

DOI

10.4049/JIMMUNOL.1400122

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24808358%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24808358%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference