Protective Efficacy of the Trivalent Pseudomonas aeruginosa Vaccine Candidate PcrV-OprI-Hcp1 in Murine Pneumonia and Burn Models (Q33822579)

29 July 2017

title

Protective Efficacy of the Trivalent Pseudomonas aeruginosa Vaccine Candidate PcrV-OprI-Hcp1 in Murine Pneumonia and Burn Models (English)

1 reference

29 July 2017

main subject

Pseudomonas aeruginosa

1 reference

Feng Yang

1

1 reference

29 July 2017

Jiang Gu

2

1 reference

29 July 2017

Liuyang Yang

3

1 reference

29 July 2017

Chen Gao

4

1 reference

29 July 2017

Haiming Jing

5

1 reference

29 July 2017

Ying Wang

6

1 reference

29 July 2017

Hao Zeng

7

1 reference

29 July 2017

Quanming Zou

8

1 reference

29 July 2017

Fenglin Lv

9

1 reference

29 July 2017

Jinyong Zhang

10

1 reference

29 July 2017

language of work or name

English

0 references

publication date

21 June 2017

1 reference

29 July 2017

1 reference

29 July 2017

volume

7

1 reference

29 July 2017

issue

1

1 reference

29 July 2017

page(s)

3957

1 reference

Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

21 June 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Sarkosyl-Induced Helical Structure of an Antimicrobial Peptide GW-Q6 Plays an Essential Role in the Binding of Surface Receptor OprI in Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Immunogenicity of Pseudomonas aeruginosa recombinant b-type fagellin as a vaccine candidate: Protective efficacy in a murine burn wound sepsis model

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Pangenome-wide and molecular evolution analyses of the Pseudomonas aeruginosa species.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Biochemical and functional characterization of the periplasmic domain of the outer membrane protein A from enterohemorrhagic Escherichia coli

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Key Residues of Outer Membrane Protein OprI Involved in Hexamer Formation and Bacterial Susceptibility to Cationic Antimicrobial Peptides

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Vaccination against respiratory Pseudomonas aeruginosa infection

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

A novel anti-PcrV antibody providing enhanced protection against Pseudomonas aeruginosa in multiple animal infection models

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Vaccine development and passive immunization for Pseudomonas aeruginosa in critically ill patients: a clinical update

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

T helper cell subsets specific for Pseudomonas aeruginosa in healthy individuals and patients with cystic fibrosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Specific humoral immune response induced by propionibacterium acnes can prevent Actinobacillus pleuropneumoniae infection in mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Evaluation of the protective immunity of a novel subunit fusion vaccine in a murine model of systemic MRSA infection

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

A randomized, placebo-controlled phase I study assessing the safety and immunogenicity of a Pseudomonas aeruginosa hybrid outer membrane protein OprF/I vaccine (IC43) in healthy volunteers

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Anti-PcrV antibody in cystic fibrosis: a novel approach targeting Pseudomonas aeruginosa airway infection

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Haemolysin coregulated protein is an exported receptor and chaperone of type VI secretion substrates

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Pseudomonas aeruginosa: new insights into pathogenesis and host defenses

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Th17-stimulating protein vaccines confer protection against Pseudomonas aeruginosa pneumonia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Development of a fourfold multiplexed opsonophagocytosis assay for pneumococcal antibodies against additional serotypes and discovery of serological subtypes in Streptococcus pneumoniae serotype 20

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Th17 cells mediate clade-specific, serotype-independent mucosal immunity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

PcrV antibody-antibiotic combination improves survival in Pseudomonas aeruginosa-infected mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Animal models of external traumatic wound infections

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Pneumonia due to Pseudomonas aeruginosa: part II: antimicrobial resistance, pharmacodynamic concepts, and antibiotic therapy.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Inescapable need for neutrophils as mediators of cellular innate immunity to acute Pseudomonas aeruginosa pneumonia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Use of the intracellular fluorescent dye CFSE to monitor lymphocyte migration and proliferation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

IL-17 is a critical component of vaccine-induced protection against lung infection by lipopolysaccharide-heterologous strains of Pseudomonas aeruginosa.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

A double-blind randomized placebo-controlled phase III study of a Pseudomonas aeruginosa flagella vaccine in cystic fibrosis patients

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Efficacy and functionality of lipoprotein OprI from Pseudomonas aeruginosa as adjuvant for a subunit vaccine against classical swine fever.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

The alternative activation pathway and complement component C3 are critical for a protective immune response against Pseudomonas aeruginosa in a murine model of pneumonia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Multi-drug resistant Pseudomonas aeruginosa outbreak in a burns unit--an infection control study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Polyclonal and monoclonal antibody therapy for experimental Pseudomonas aeruginosa pneumonia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Opsonophagocytic killing antibody to Pseudomonas aeruginosa mucoid exopolysaccharide in older noncolonized patients with cystic fibrosis.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Prevalence, risk factors, and mortality for ventilator-associated pneumonia in middle-aged, old, and very old critically ill patients*.

4 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

Pharmacokinetics and safety of panobacumab: specific adjunctive immunotherapy in critical patients with nosocomial Pseudomonas aeruginosa O11 pneumonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

Determination of protein oligomerization state: two approaches based on glutaraldehyde crosslinking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

Fusion expression and immunogenicity of Bordetella pertussis PTS1-FHA protein: implications for the vaccine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

AhR sensing of bacterial pigments regulates antibacterial defence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

The in vitro displacement of adsorbed model antigens from aluminium-containing adjuvants by interstitial proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

A fusion protein vaccine containing OprF epitope 8, OprI, and type A and B flagellins promotes enhanced clearance of nonmucoid Pseudomonas aeruginosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

Effect of anti-OprF-OprI immunoglobulin on APACHE II score in a porcine two-hit model of hemorrhagic shock/resuscitation and pseudomonas aeruginosa sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

PcrV antibody protects multi-drug resistant Pseudomonas aeruginosa induced acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

Clinical study to assess the immunogenicity and safety of a recombinant Pseudomonas aeruginosa OprF-OprI vaccine in burn patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

Recombinant OprF-OprI as a vaccine against Pseudomonas aeruginosa infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

Improved outcome of chronic Pseudomonas aeruginosa lung infection is associated with induction of a Th1-dominated cytokine response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

Mucosal prime-boost vaccination for tuberculosis based on TLR triggering OprI lipoprotein from Pseudomonas aeruginosa fused to mycolyl-transferase Ag85A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-04029-5

Lipoprotein I, a TLR2/4 ligand modulates Th2-driven allergic immune responses

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5479855

Safety and pharmacokinetics of an anti-PcrV PEGylated monoclonal antibody fragment in mechanically ventilated patients colonized with Pseudomonas aeruginosa

29 October 2018

1 reference

12 December 2020

Candida albicans impairs macrophage function and facilitates Pseudomonas aeruginosa pneumonia in rat

1 reference

12 December 2020

Immunoprophylaxis against klebsiella and pseudomonas aeruginosa infections. The Federal Hyperimmune Immunoglobulin Trial Study Group

1 reference

12 December 2020

CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung

1 reference

12 December 2020

Phase separation of myelin sheath in Triton X-114 solution: predominant localization of the 21.5-kDa isoform of myelin basic protein in the lipid raft-associated domain

1 reference

12 December 2020

Passive anti-PcrV treatment protects burned mice against Pseudomonas aeruginosa challenge

1 reference

12 December 2020

The bicinchoninic acid (BCA) assay for protein quantitation

1 reference

12 December 2020

10.1038/S41598-017-04029-5

Identifiers

DOI

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference