Sclerostin antibody inhibits skeletal deterioration due to reduced mechanical loading (Q33825376)

29 July 2017

Sclerostin antibody inhibits skeletal deterioration due to reduced mechanical loading (English)

1 reference

29 July 2017

1 reference

10

Mary L Bouxsein

1 reference

29 July 2017

Jordan M Spatz

1

1 reference

29 July 2017

Rachel Ellman

2

1 reference

29 July 2017

Alison M Cloutier

3

1 reference

29 July 2017

Leeann Louis

4

1 reference

29 July 2017

Miranda van Vliet

5

1 reference

29 July 2017

Larry J Suva

6

1 reference

29 July 2017

Denise Dwyer

7

1 reference

29 July 2017

Marina Stolina

8

1 reference

29 July 2017

Hua Zhu Ke

9

1 reference

29 July 2017

1 April 2013

1 reference

Journal of Bone and Mineral Research

29 July 2017

1 reference

29 July 2017

28

1 reference

29 July 2017

4

1 reference

29 July 2017

865-874

1 reference

Sclerostin and Dickkopf-1 as therapeutic targets in bone diseases

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Anti-sclerostin antibody and mechanical loading appear to influence metaphyseal bone independently in rats

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Forming functional fat: a growing understanding of adipocyte differentiation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Matrix-embedded cells control osteoclast formation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Caloric restriction leads to high marrow adiposity and low bone mass in growing mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Wnt and PPARgamma signaling in osteoblastogenesis and adipogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Patients with high bone mass phenotype exhibit enhanced osteoblast differentiation and inhibition of adipogenesis of human mesenchymal stem cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Transforming growth factor beta2 inhibits adipocyte differentiation induced by skeletal unloading in rat bone marrow stroma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Hindlimb unloading rodent model: technical aspects

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Inhibition of adipogenesis by Wnt signaling

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Bone histomorphometry: standardization of nomenclature, symbols and units (summary of proposed system).

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076162

Benefits for bone from resistance exercise and nutrition in long-duration spaceflight: Evidence from biochemistry and densitometry

4 July 2018

1 reference

Ultrastructural changes in osteocytes in microgravity conditions

21 January 2018

1 reference

Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss.

21 January 2018

1 reference

Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling.

21 January 2018

1 reference

Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats

21 January 2018

1 reference

Sclerostin antibody increases bone mass by stimulating bone formation and inhibiting bone resorption in a hindlimb-immobilization rat model.

21 January 2018

1 reference

Early response of bone marrow osteoprogenitors to skeletal unloading and sclerostin antibody

21 January 2018

1 reference

Growing C57Bl/6 mice increase whole bone mechanical properties by increasing geometric and material properties.

21 January 2018

1 reference

Trabecular Bone Tissue Strains in the Healthy and Osteoporotic Human Femur

21 January 2018

1 reference

The influence of immobilization on osteocyte morphology: osteocyte differential count and electron microscopical studies

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23109229

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Simulated resistance training, but not alendronate, increases cortical bone formation and suppresses sclerostin during disuse

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23109229

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/JBMR.1807

1 reference

29 July 2017

1 reference

29 July 2017

1 reference