Sac-1004, a vascular leakage blocker, reduces cerebral ischemia-reperfusion injury by suppressing blood-brain barrier disruption and inflammation (Q33827436)

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English	Sac-1004, a vascular leakage blocker, reduces cerebral ischemia-reperfusion injury by suppressing blood-brain barrier disruption and inflammation	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Sac-1004, a vascular leakage blocker, reduces cerebral ischemia-reperfusion injury by suppressing blood-brain barrier disruption and inflammation (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

reperfusion injury

1 reference

based on heuristic

inferred from title

cerebral infarction

1 reference

based on heuristic

inferred from title

blood–brain barrier

1 reference

based on heuristic

inferred from title

author name string

Haiying Zhang

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28645333%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Joon Ha Park

2

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1 June 2020

Sony Maharjan

3

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1 June 2020

Jeong Ae Park

4

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1 June 2020

Kyu-Sung Choi

5

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1 June 2020

Hyojin Park

6

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1 June 2020

Yoonjeong Jeong

7

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1 June 2020

Ji Hyeon Ahn

8

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1 June 2020

In Hye Kim

9

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1 June 2020

Jae-Chul Lee

10

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1 June 2020

Jeong Hwi Cho

11

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1 June 2020

In-Kyu Lee

12

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1 June 2020

Choong Hyun Lee

13

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1 June 2020

Young-Myeong Kim

15

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1 June 2020

Young-Ger Suh

16

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1 June 2020

Moo-Ho Won

17

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1 June 2020

language of work or name

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publication date

23 June 2017

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29 July 2017

Journal of Neuroinflammation

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1 June 2020

14

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1 June 2020

1

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1 June 2020

122

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28645333%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Melatonin Preserves Blood-Brain Barrier Integrity and Permeability via Matrix Metalloproteinase-9 Inhibition

1 reference

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4 July 2018

Sac-1004, a Pseudo-Sugar Derivative of Cholesterol, Restores Erectile Function through Reconstruction of Nonleaky and Functional Cavernous Angiogenesis in the Streptozotocin Induced Diabetic Mouse

1 reference

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4 July 2018

Imaging Neuroinflammation - from Bench to Bedside

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4 July 2018

Blood-brain barrier breakdown involves four distinct stages of vascular damage in various models of experimental focal cerebral ischemia

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The impact of microglial activation on blood-brain barrier in brain diseases.

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4 July 2018

Combined effect of vascular-leakage-blocker Sac-1004 and antiangiogenic drug sunitinib on tumor angiogenesis

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Endothelial barrier antigen-immunoreactivity is conversely associated with blood-brain barrier dysfunction after embolic stroke in rats

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Development, maintenance and disruption of the blood-brain barrier

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Neuroprotective effect of a new synthetic aspirin-decursinol adduct in experimental animal models of ischemic stroke

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Rk1, a ginsenoside, is a new blocker of vascular leakage acting through actin structure remodeling

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Microglia and ischemic stroke: a double-edged sword

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Inflammatory events at blood-brain barrier in neuroinflammatory and neurodegenerative disorders: implications for clinical disease

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Neuroprotection for stroke: current status and future perspectives

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4 July 2018

Tight junction in blood-brain barrier: an overview of structure, regulation, and regulator substances

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Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in stroke

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Breaking the barrier in stroke: what should we know? A mini-review.

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4 July 2018

Interleukin-1β-induced barrier dysfunction is signaled through PKC-θ in human brain microvascular endothelium

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Heart disease and stroke statistics--2012 update: a report from the American Heart Association

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Current therapies in ischemic stroke. Part A. Recent developments in acute stroke treatment and in stroke prevention

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Interleukin-1 and stroke: biomarker, harbinger of damage, and therapeutic target

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Blood-brain barrier breakdown in acute and chronic cerebrovascular disease

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4 July 2018

In vitro models of the blood-brain barrier

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4 July 2018

Impairment of brain endothelial glucose transporter by methamphetamine causes blood-brain barrier dysfunction

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The dual role of the neuroinflammatory response after ischemic stroke: modulatory effects of hypothermia

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Microglial activation and chronic neurodegeneration

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Mechanisms underlying inflammation in neurodegeneration

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Reperfusion and neurovascular dysfunction in stroke: from basic mechanisms to potential strategies for neuroprotection

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Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

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Inflammatory mechanisms in ischemic stroke: therapeutic approaches

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Construction of mutant TKGFP for real-time imaging of temporal dynamics of HIF-1 signal transduction activity mediated by hypoxia and reoxygenation in tumors in living mice

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Structure and function of the blood-brain barrier

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4 July 2018

CD47 gene knockout protects against transient focal cerebral ischemia in mice

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Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke

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Tumor necrosis factor and stroke: role of the blood-brain barrier

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The inflammatory response in stroke

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Inflammation in stroke and focal cerebral ischemia.

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Inflammation following stroke.

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Interleukin-1beta -induced changes in blood-brain barrier permeability, apparent diffusion coefficient, and cerebral blood volume in the rat brain: a magnetic resonance study.

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Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in rats.

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4 July 2018

Reperfusion-induced injury to the blood-brain barrier after middle cerebral artery occlusion in rats

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The structure and function of the blood-brain barrier

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Brain metabolism: a perspective from the blood-brain barrier

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A mouse model of focal cerebral ischemia for screening neuroprotective drug effects.

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4 July 2018

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21 January 2018

CXCR4 antagonist AMD3100 protects blood-brain barrier integrity and reduces inflammatory response after focal ischemia in mice

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21 January 2018

Sac-1004, a novel vascular leakage blocker, enhances endothelial barrier through the cAMP/Rac/cortactin pathway.

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https://api.crossref.org/works/10.1186%2FS12974-017-0897-3

21 January 2018

ERK is an anti-inflammatory signal that suppresses expression of NF-kappaB-dependent inflammatory genes by inhibiting IKK activity in endothelial cells.

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21 January 2018

Tissue inhibitor of metalloproteinases protect blood-brain barrier disruption in focal cerebral ischemia.

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21 January 2018

Secretion of interleukin-1beta by astrocytes mediates endothelin-1 and tumour necrosis factor-alpha effects on human brain microvascular endothelial cell permeability.

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21 January 2018

Inflammatory response after ischemic stroke: a USPIO-enhanced MRI study in patients

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Long-Term Exercise Improves Memory Deficits via Restoration of Myelin and Microvessel Damage, and Enhancement of Neurogenesis in the Aged Gerbil Hippocampus After Ischemic Stroke.

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21 January 2018

Imaging neuroinflammation in ischemic stroke and in the atherosclerotic vascular disease.

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21 January 2018

Matrix metalloproteinase-2 and metalloproteinase-9 activities are associated with blood-brain barrier dysfunction in an animal model of severe sepsis.

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21 January 2018

Microglia potentiate damage to blood-brain barrier constituents: improvement by minocycline in vivo and in vitro.

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21 January 2018

Glia-induced reversible disruption of blood-brain barrier integrity and neuropathological response of the neurovascular unit.

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21 January 2018

Chronic interleukin-1beta expression in mouse brain leads to leukocyte infiltration and neutrophil-independent blood brain barrier permeability without overt neurodegeneration

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12 December 2020

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Decrease in dystrophin expression prior to disruption of brain-blood barrier within the rat piriform cortex following status epilepticus

1 reference

https://pubmed.ncbi.nlm.nih.gov/28645333

12 December 2020

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Functional assessments in mice and rats after focal stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/28645333

12 December 2020

based on heuristic

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Ultrastructural changes during wood decay by Antrodiella sp. RK1

1 reference

https://pubmed.ncbi.nlm.nih.gov/28645333

12 December 2020

based on heuristic

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10.1186/S12974-017-0897-3

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Europe PubMed Central

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1 June 2020

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1 June 2020

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1 June 2020

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