Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes (Q33828702)

29 July 2017

title

Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes (English)

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29 July 2017

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Lei-lei Chen

1

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29 July 2017

Jun-chao Wu

2

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29 July 2017

Lin-hui Wang

3

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29 July 2017

Jin Wang

4

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29 July 2017

Zheng-hong Qin

5

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29 July 2017

Marian Difiglia

6

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29 July 2017

Fang Lin

7

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29 July 2017

publication date

23 January 2012

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Acta Pharmacologica Sinica

29 July 2017

published in

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29 July 2017

volume

33

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29 July 2017

issue

3

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29 July 2017

page(s)

385-392

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Autophagy failure in Alzheimer's disease--locating the primary defect

29 July 2017

cites work

1 reference

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Early alterations of autophagy in Huntington disease-like mice

28 July 2018

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α-Synuclein impairs macroautophagy: implications for Parkinson's disease.

28 July 2018

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In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

28 July 2018

1 reference

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Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice

28 July 2018

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Autophagy protects the rotenone-induced cell death in alpha-synuclein overexpressing SH-SY5Y cells

28 July 2018

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Rapamycin protects against rotenone-induced apoptosis through autophagy induction

28 July 2018

1 reference

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Huntington's disease: degradation of mutant huntingtin by autophagy

28 July 2018

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Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

28 July 2018

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28 July 2018

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Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease

28 July 2018

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Is Huntington's a glutamine storage disease?

28 July 2018

1 reference

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Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease

28 July 2018

1 reference

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

28 July 2018

1 reference

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Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

28 July 2018

1 reference

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077128

Insights into glutamate transport regulation in human astrocytes: cloning of the promoter for excitatory amino acid transporter 2 (EAAT2).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077128

Selective blockade of astrocytic glutamate transporter GLT-1 with dihydrokainate prevents neuronal death during ouabain treatment of astrocyte/neuron cocultures

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077128

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

28 July 2018

1 reference

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Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

28 July 2018

1 reference

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Glutamate transporters in neurologic disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077128

Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077128

Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

28 July 2018

1 reference

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Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.162

Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.162

Autophagy regulates the processing of amino terminal huntingtin fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.162

High efficiency adenovirus-mediated expression of truncated N-terminal huntingtin fragment (htt552) in primary rat astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.162

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.162

Differential activities of the ubiquitin-proteasome system in neurons versus glia may account for the preferential accumulation of misfolded proteins in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.162

Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.162

Global changes to the ubiquitin system in Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.162

Interaction of Huntington disease protein with transcriptional activator Sp1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.162

Enhanced degradation of mutant huntingtin by rho kinase inhibition is mediated through activation of proteasome and macroautophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.162

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.162

Monitoring autophagy in Alzheimer's disease and related neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.162

Rapamycin alleviates toxicity of different aggregate-prone proteins

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077128

Clearance of mutant huntingtin

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22266730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/APS.2011.162

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference