Drug trials in children: problems and the way forward (Q33836061)

29 July 2017

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title

Drug trials in children: problems and the way forward (English)

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29 July 2017

I Choonara

3

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author name string

S Conroy

series ordinal

1

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29 July 2017

J McIntyre

series ordinal

2

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29 July 2017

T Stephenson

series ordinal

4

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29 July 2017

language of work or name

English

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publication date

1 February 2000

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British Journal of Clinical Pharmacology

29 July 2017

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29 July 2017

49

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29 July 2017

2

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29 July 2017

93-97

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Status of new medicines approved by the European Medicines Evaluation Agency regarding paediatric use.

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Paediatric prescribing: using unlicensed drugs and medicines outside their licensed indications

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Respiratory depression in children receiving diazepam for acute seizures: a prospective study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Unlicensed and off label drug use in neonates

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

4 July 2018

Licensing of medicines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Induction of CYP1A2 activity by carbamazepine in children using the caffeine breath test

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Unlicensed and off label drug use in paediatric wards: prospective study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Enhanced drug metabolism in young children with cystic fibrosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Drug toxicity and surveillance in children

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Morphine, morphine-6-glucuronide and morphine-3-glucuronide pharmacokinetics in newborn infants receiving diamorphine infusions

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Inhibition of caffeine metabolism by ciprofloxacin in children with cystic fibrosis as measured by the caffeine breath test

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

A prospective study of the adverse effects of midazolam on withdrawal in critically ill children

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Lorazepam versus diazepam in the acute treatment of epileptic seizures and status epilepticus

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Paracetamol poisoning in children and hepatotoxicity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Valproate metabolites in serum and urine during antiepileptic therapy in children with infantile spasms: abnormal metabolite pattern associated with reversible hepatotoxicity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

The human hepatic cytochromes P450 involved in drug metabolism

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Morphine metabolism in neonates and infants

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Steady-state plasma concentrations of midazolam in critically ill infants and children.

4 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2000.00125.X

Population pharmacokinetics of midazolam in neonates.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014901

Use of "off-label" and unlicensed drugs in paediatric intensive care unit

29 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2000.00125.X

Tenfold errors in administration of drug doses: a neglected iatrogenic disease in pediatrics

21 January 2018

1 reference

12 December 2020

Urinary excretion of 6 beta-hydroxycortisol and the time course measurement of enzyme induction in man

1 reference

12 December 2020

Children are not small adults

1 reference

12 December 2020

Chloramphenicol in the newborn infant. A physiologic explanation of its toxicity when given in excessive doses

1 reference

12 December 2020

Effect of growth hormone therapy in growth hormone-deficient children on cytochrome P-450-dependent 3-N-demethylation of caffeine as measured by the caffeine 13CO2 breath test

1 reference

12 December 2020

10.1046/J.1365-2125.2000.00125.X

Identifiers

DOI

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29 July 2017

1 reference

29 July 2017

1 reference