Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes. (Q33837060)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15899862%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

title

Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes (English)

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11 January 2020

3

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Kenna R Mills

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Joan S Brugge

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11 January 2020

author name string

Mauricio J Reginato

1

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11 January 2020

Danielle K Lynch

4

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11 January 2020

Azad Bonni

5

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11 January 2020

Senthil K Muthuswamy

6

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11 January 2020

language of work or name

English

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publication date

1 June 2005

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Molecular and Cellular Biology

11 January 2020

published in

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11 January 2020

volume

25

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11 January 2020

issue

11

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11 January 2020

page(s)

4591-4601

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Bim is an apoptosis sensor that responds to loss of survival signals delivered by epidermal growth factor but not those provided by integrins

11 January 2020

cites work

1 reference

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Bim is a suppressor of Myc-induced mouse B cell leukemia

4 July 2018

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Cell death: critical control points

4 July 2018

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Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover

4 July 2018

1 reference

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Role of Bim in the survival pathway induced by Raf in epithelial cells

4 July 2018

1 reference

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Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner

4 July 2018

1 reference

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Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

4 July 2018

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4 July 2018

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Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

4 July 2018

1 reference

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Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways

4 July 2018

1 reference

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Tube morphogenesis: making and shaping biological tubes

4 July 2018

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Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation

4 July 2018

1 reference

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Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts

4 July 2018

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Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

4 July 2018

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FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

4 July 2018

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Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim

4 July 2018

1 reference

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Erk MAP kinase regulates branching morphogenesis in the developing mouse kidney

4 July 2018

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

4 July 2018

1 reference

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ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

4 July 2018

1 reference

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

4 July 2018

1 reference

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Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors

4 July 2018

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BH3-Only proteins-essential initiators of apoptotic cell death

4 July 2018

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Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

4 July 2018

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Regulation of programmed cell death by basement membranes in embryonic development

4 July 2018

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Essential role of biliary glycoprotein (CD66a) in morphogenesis of the human mammary epithelial cell line MCF10F.

4 July 2018

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Submandibular gland morphogenesis: stage-specific expression of TGF-alpha/EGF, IGF, TGF-beta, TNF, and IL-6 signal transduction in normal embryonic mice and the phenotypic effects of TGF-beta2, TGF-beta3, and EGF-r null mutations

4 July 2018

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BMP signaling plays a role in visceral endoderm differentiation and cavitation in the early mouse embryo.

4 July 2018

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Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology

4 July 2018

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Bim: a novel member of the Bcl-2 family that promotes apoptosis

4 July 2018

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Apoptosis in the terminal endbud of the murine mammary gland: a mechanism of ductal morphogenesis.

4 July 2018

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Role of laminin-1 and TGF-beta 3 in acinar differentiation of a human submandibular gland cell line (HSG).

4 July 2018

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Apoptosis during an early stage of nephrogenesis induces renal hypoplasia in bcl-2-deficient mice

4 July 2018

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Estrogen and progesterone receptor and c-erbB-2 oncoprotein analysis in pure in situ breast carcinoma: an immunohistochemical study.

4 July 2018

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Fulminant metanephric apoptosis and abnormal kidney development in bcl-2-deficient mice

4 July 2018

1 reference

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Signals for death and survival: A two-step mechanism for cavitation in the vertebrate embryo

4 July 2018

1 reference

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Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis

4 July 2018

1 reference

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The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140636

Ras activation in human breast cancer

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140636

The ERK-1/2 signaling pathway is involved in the stimulation of branching morphogenesis of fetal mouse submandibular glands by EGF

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15899862

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Investigation of the Mek-MAP kinase-Rsk pathway in human breast cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15899862

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Influence of microenvironment on mammary epithelial cell survival in primary culture

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15899862

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.25.11.4591-4601.2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15899862%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15899862%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

PubMed publication ID

15899862

1 reference