The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma (Q33839970)

29 July 2017

The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma (English)

1 reference

Leticia Quintanilla-Martinez

29 July 2017

8

object named as

Leticia Quintanilla-Martinez

0 references

author name string

Konstanze Pechloff

1

1 reference

29 July 2017

Julian Holch

2

1 reference

29 July 2017

Uta Ferch

3

1 reference

29 July 2017

Marc Schweneker

4

1 reference

29 July 2017

Kristina Brunner

5

1 reference

29 July 2017

Markus Kremer

6

1 reference

29 July 2017

Tim Sparwasser

7

1 reference

29 July 2017

Ursula Zimber-Strobl

9

1 reference

29 July 2017

Berthold Streubel

10

1 reference

29 July 2017

Andreas Gewies

11

1 reference

29 July 2017

Christian Peschel

12

1 reference

29 July 2017

Jürgen Ruland

13

1 reference

29 July 2017

language of work or name

English

0 references

publication date

3 May 2010

1 reference

Journal of Experimental Medicine

29 July 2017

1 reference

29 July 2017

207

1 reference

29 July 2017

5

1 reference

29 July 2017

1031-1044

1 reference

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

The lymphoma-associated fusion tyrosine kinase ITK-SYK requires pleckstrin homology domain-mediated membrane localization for activation and cellular transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Pathobiology of mature T-cell lymphomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Chromosomal abnormalities in cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Overexpression of Syk tyrosine kinase in peripheral T-cell lymphomas.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Distinct roles for Syk and ZAP-70 during early thymocyte development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Peripheral T-cell lymphomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Mechanisms of B-cell lymphoma pathogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Tec family kinases in T lymphocyte development and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Jurkat T cells and development of the T-cell receptor signalling paradigm

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Location is everything: lipid rafts and immune cell signaling.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Structure and function of Syk protein-tyrosine kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Adapter proteins in lymphocyte antigen-receptor signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Interaction of SLP adaptors with the SH2 domain of Tec family kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Identification of the SH2 domain binding protein of Bruton's tyrosine kinase as BLNK--functional significance of Btk-SH2 domain in B-cell antigen receptor-coupled calcium signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Selection of the T cell repertoire.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

B lymphocyte-specific, Cre-mediated mutagenesis in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867290

Prognostic factors and treatment of patients with T-cell non-Hodgkin lymphoma: the M. D. Anderson Cancer Center experience

5 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20092042

FLT3-ITD and tyrosine kinase domain mutants induce 2 distinct phenotypes in a murine bone marrow transplantation model

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20092042

T cell progenitors emerge earlier than B cell progenitors in the murine fetal liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20092042

A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20092042

Canonical NF-κB Activity, Dispensable for B Cell Development, Replaces BAFF-Receptor Signals and Promotes B Cell Proliferation upon Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20092042

Novel t(5;9)(q33;q22) fuses ITK to SYK in unspecified peripheral T-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20092042

Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20092042

Analysis of rearranged T-cell receptor beta-chain genes by polymerase chain reaction (PCR) DNA sequencing and automated high resolution PCR fragment analysis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20439541

12 December 2020

inferred from PubMed ID database lookup

Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20439541

12 December 2020

inferred from PubMed ID database lookup

MALT1 directs B cell receptor–induced canonical nuclear factor-κB signaling selectively to the c-Rel subunit

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20439541

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1084/JEM.20092042

1 reference

release_d2nwo5eib5emdlbbjmjv65pqka

29 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/d2nwo5eib5emdlbbjmjv65pqka

24 November 2022

mapped directly with Wikidata item

PMCID

2867290

1 reference

29 July 2017

1 reference