Jurkat T cells and development of the T-cell receptor signalling paradigm (Q35730832)

9 August 2017

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title

Jurkat T cells and development of the T-cell receptor signalling paradigm (English)

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9 August 2017

2

Arthur Weiss

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9 August 2017

Robert T Abraham

1

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9 August 2017

1 April 2004

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Nature Reviews Immunology

9 August 2017

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9 August 2017

4

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9 August 2017

4

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9 August 2017

301-308

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Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line

9 August 2017

1 reference

Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor

31 March 2020

1 reference

Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex

31 March 2020

1 reference

Presence of T 145 on cytolytic T cell lines and their lectin-resistant mutants.

31 March 2020

1 reference

Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium

31 March 2020

1 reference

Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer.

31 March 2020

1 reference

Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line

31 March 2020

1 reference

Activation rules: the two-signal theories of immune activation

31 March 2020

1 reference

Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester

31 March 2020

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Relationship between parathyroid hormone secretion and cytosolic calcium concentration in dispersed bovine parathyroid cells

31 March 2020

1 reference

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator

31 March 2020

1 reference

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores

31 March 2020

1 reference

Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor.

31 March 2020

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At least two non-antigen-binding molecules are required for signal transduction by the T-cell antigen receptor

31 March 2020

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A transfected human muscarinic receptor fails to substitute for the T cell antigen receptor complex in CD2-initiated signal transduction

31 March 2020

1 reference

A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA.

31 March 2020

1 reference

Molecular interactions, T-cell subsets and a role of the CD4/CD8:p56lck complex in human T-cell activation

31 March 2020

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The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

31 March 2020

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A 20-kDa protein associated with the murine T-cell antigen receptor is phosphorylated in response to activation by antigen or concanavalin A.

31 March 2020

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Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

31 March 2020

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Antigen receptor tail clue.

31 March 2020

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The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways

31 March 2020

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Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides

31 March 2020

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The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules.

31 March 2020

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T cell activation by clustered tyrosine kinases

31 March 2020

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T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins.

31 March 2020

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T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation

31 March 2020

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Tyrosine phosphorylation in T cells is regulated by phosphatase activity: studies with phenylarsine oxide

31 March 2020

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Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor

31 March 2020

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Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production

31 March 2020

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Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

31 March 2020

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Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction

31 March 2020

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The Role of Tyrosine Protein Phosphorylation in Lymphocyte Activation

31 March 2020

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Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation

31 March 2020

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ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

31 March 2020

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Signal transduction by the TCR for antigen

31 March 2020

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Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins

31 March 2020

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LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

31 March 2020

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CD3 stimulation causes phosphorylation of phospholipase C-gamma 1 on serine and tyrosine residues in a human T-cell line

31 March 2020

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Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1.

31 March 2020

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Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

31 March 2020

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Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

31 March 2020

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LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

31 March 2020

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Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

31 March 2020

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Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line

31 March 2020

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Syk mutation in Jurkat E6-derived clones results in lack of p72syk expression

31 March 2020

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Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation

31 March 2020

1 reference

Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell line

31 March 2020

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Mutant T cell lines as model systems for the dissection of T cell antigen receptor signaling pathways

31 March 2020

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Antiproliferative action of interferon-α requires components of T-cell-receptor signalling

31 March 2020

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A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells

31 March 2020

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A requirement for CARMA1 in TCR-induced NF-kappa B activation

31 March 2020

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T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression

31 March 2020

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PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models.

31 March 2020

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Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

31 March 2020

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The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase

31 March 2020

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Signaling pathways of D3-phosphoinositide-binding kinases in T cells and their regulation by PTEN.

31 March 2020

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Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse

31 March 2020

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ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency

31 March 2020

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Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

31 March 2020

1 reference

Gene targeting and somatic cell genetics--a rebirth or a coming of age?

31 March 2020

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Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line.

31 March 2020

1 reference

Regulatory and signaling properties of the Vav family

31 March 2020

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VAV proteins as signal integrators for multi-subunit immune-recognition receptors

31 March 2020

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SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site

31 March 2020

1 reference

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

31 March 2020

1 reference

A system for stable expression of short interfering RNAs in mammalian cells

31 March 2020

1 reference

Activation of the interferon system by short-interfering RNAs

31 March 2020

1 reference

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.

31 March 2020

1 reference

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

31 March 2020

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Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

31 March 2020

1 reference

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI1330

1 reference

9 August 2017

1 reference

PubMed ID

15057788