Carcinogenesis in mouse and human cells: parallels and paradoxes (Q33846175)

29 July 2017

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title

Carcinogenesis in mouse and human cells: parallels and paradoxes (English)

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29 July 2017

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Balmain A

1

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PubMed ID

10688857

29 July 2017

Harris CC

series ordinal

2

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PubMed ID

10688857

29 July 2017

language of work or name

English

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publication date

1 March 2000

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29 July 2017

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29 July 2017

21

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29 July 2017

3

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29 July 2017

371-377

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A genetic model for colorectal tumorigenesis

29 July 2017

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

The ras gene family and human carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Nonrandom duplication of the chromosome bearing a mutated Ha-ras-1 allele in mouse skin tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Allelotyping of butadiene-induced lung and mammary adenocarcinomas of B6C3F1 mice: frequent losses of heterozygosity in regions homologous to human tumor-suppressor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Inactivations of p16INK4a-alpha, p16INK4a-beta and p15INK4b genes in 2',3'-dideoxycytidine- and 1,3-butadiene-induced murine lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

A cell cycle regulator potentially involved in genesis of many tumor types

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Structure and function of telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Telomerase catalytic subunit homologs from fission yeast and human

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Creation of human tumour cells with defined genetic elements

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Telomere maintenance mechanisms and cellular immortalization.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Hypervariable ultra-long telomeres in mice

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Telomere length regulation during postnatal development and ageing in Mus spretus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Distinct genetic loci control development of benign and malignant skin tumours in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Different susceptibility to lung tumorigenesis in mice with an identical Kras2 intron 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

A metabolite of the carcinogen 7,12-dimethylbenz[a]anthracene that reacts predominantly with adenine residues in DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Mutational spectra in the lacl gene in skin from 7,12-dimethylbenz[a]anthracene-treated and untreated transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Polycyclic aromatic hydrocarbons: correlations between DNA adducts and ras oncogene mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

High frequency of codon 61 K-ras A-->T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Specific mutational spectrum of dimethylnitrosamine in the lacI transgene of Big Blue C57BL/6 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Nucleotide excision repair and human syndromes

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

p53 protects against skin cancer induction by UV-B radiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Dietary polyunsaturated fatty acids and cancers of the breast and colorectum: emerging evidence for their role as risk modifiers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Nutrition and dietary carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Approaches to cancer prevention based on an understanding of N-nitrosamine carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

DNA methylation: past, present and future directions

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Molecular epidemiology: recent advances and future directions

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

p53 mutations in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Molecular epidemiology of human cancer

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Stabilization of beta-catenin by genetic defects in melanoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

A common human skin tumour is caused by activating mutations in beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Sunlight and the onset of skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Frequent clones of p53-mutated keratinocytes in normal human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

The generation of a library of PCR-analyzed microsatellite variants for genetic mapping of the mouse genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Cancer resistance genes in mice: models for the study of tumour modifiers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Manipulating the germline: its impact on the study of carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

Sunburn and p53 in the onset of skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.371

21 January 2018

Identifiers

DOI

10.1093/CARCIN/21.3.371

1 reference

29 July 2017

1 reference

PubMed ID

10688857