p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis (Q33862956)

29 July 2017

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis (English)

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29 July 2017

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7

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29 July 2017

Chin L

1

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29 July 2017

Artandi SE

2

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29 July 2017

Shen Q

3

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29 July 2017

Tam A

4

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29 July 2017

Lee SL

5

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29 July 2017

Gottlieb GJ

6

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29 July 2017

DePinho RA

8

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29 July 2017

language of work or name

English

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publication date

1 May 1999

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29 July 2017

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29 July 2017

97

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29 July 2017

4

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29 July 2017

527-538

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

29 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Telomere elongation in immortal human cells without detectable telomerase activity

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Telomeres and senescence: the history, the experiment, the future

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

The serial cultivation of human diploid cell strains

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Telomere shortening in mTR-/- embryos is associated with failure to close the neural tube

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Oncogenic forms of p53 inhibit p53-regulated gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Specific association of human telomerase activity with immortal cells and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

p53, the cellular gatekeeper for growth and division

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

An alternative pathway for yeast telomere maintenance rescues est1- senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Myc family oncoproteins function through a common pathway to transform normal cells in culture: cross-interference by Max and trans-acting dominant mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Severe growth defect in mouse cells lacking the telomerase RNA component.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Signaling to p53: breaking the MDM2-p53 circuit

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

A subset of p53-deficient embryos exhibit exencephaly

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

A role for both RB and p53 in the regulation of human cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

DNA damage induces phosphorylation of the amino terminus of p53

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Control of telomere length by the human telomeric protein TRF1

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

TRF2 Protects Human Telomeres from End-to-End Fusions

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980762-X

7 January 2021

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/S0092-8674(00)80762-X

Identifiers

DOI

10.1016/S0092-8674(00)80762-X

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29 July 2017

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