The B7/CD28/CTLA4 T-cell activation pathway. Implications for inflammatory lung disease (Q33850990)

29 July 2017

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title

The B7/CD28/CTLA4 T-cell activation pathway. Implications for inflammatory lung disease (English)

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29 July 2017

J M Green

1

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29 July 2017

publication date

1 March 2000

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American Journal of Respiratory Cell and Molecular Biology

29 July 2017

published in

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29 July 2017

volume

22

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29 July 2017

issue

3

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29 July 2017

page(s)

261-264

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A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

29 July 2017

cites work

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CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

21 January 2018

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Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy

21 January 2018

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T-cell proliferation involving the CD28 pathway is associated with cyclosporine-resistant interleukin 2 gene expression

21 January 2018

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Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.

21 January 2018

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https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1.

21 January 2018

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https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

B70 antigen is a second ligand for CTLA-4 and CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

Cloning of B7-2: a CTLA-4 Counter-Receptor That Costimulates Human T Cell Proliferation

21 January 2018

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Uncovering of Functional Alternative CTLA-4 Counter-Receptor in B7-Deficient Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

CTLA-4 is a second receptor for the B cell activation antigen B7

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

A new member of the immunoglobulin superfamily--CTLA-4

21 January 2018

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CTLA-4 can function as a negative regulator of T cell activation

21 January 2018

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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

21 January 2018

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

1 reference

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B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo

21 January 2018

1 reference

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Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells

21 January 2018

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Enhancement of antitumor immunity by CTLA-4 blockade

21 January 2018

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B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

21 January 2018

1 reference

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CTLA-4 ligands are required to induce an in vivo interleukin 4 response to a gastrointestinal nematode parasite

21 January 2018

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Limited role of CD28-mediated signals in T helper subset differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

Making the T cell receptor go the distance: a topological view of T cell activation

21 January 2018

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https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

The B7 and CD28 receptor families

21 January 2018

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https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

Upstream-downstream: CD28 cosignaling pathways and T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells

21 January 2018

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https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

Molecular basis of T cell inactivation by CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

Cytotoxic T lymphocyte antigen 4 (CTLA-4) engagement delivers an inhibitory signal through the membrane-proximal region in the absence of the tyrosine motif in the cytoplasmic tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

B7-1 or B7-2 is required to produce the lymphoproliferative phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.22.3.F179

21 January 2018

Identifiers

DOI

10.1165/AJRCMB.22.3.F179

1 reference

29 July 2017

1 reference