HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2 (Q33851502)

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26 January 2020

title

HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2 (English)

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26 January 2020

6

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26 January 2020

Karen E Ocwieja

1

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26 January 2020

Gregory Towers

8

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26 January 2020

Renate König

11

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26 January 2020

Frederic D. Bushman

14

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26 January 2020

author name string

Troy L Brady

2

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26 January 2020

Keshet Ronen

3

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26 January 2020

Alyssa Huegel

4

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26 January 2020

Shoshannah L Roth

5

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26 January 2020

Leo C James

7

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26 January 2020

John A T Young

9

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26 January 2020

Sumit K Chanda

10

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26 January 2020

Nirav Malani

12

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26 January 2020

Charles C Berry

13

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26 January 2020

language of work or name

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10 March 2011

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26 January 2020

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26 January 2020

volume

7

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26 January 2020

issue

3

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26 January 2020

page(s)

e1001313

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Creative Commons Attribution 4.0 International

26 January 2020

copyright license

start time

10 March 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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SAGA and a novel Drosophila export complex anchor efficient transcription and mRNA export to NPC.

5 July 2018

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Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells

5 July 2018

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LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

5 July 2018

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HIV integration site selection: analysis by massively parallel pyrosequencing reveals association with epigenetic modifications

5 July 2018

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5 July 2018

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Selection of target sites for mobile DNA integration in the human genome

5 July 2018

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Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C).

5 July 2018

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Retroviral DNA integration: viral and cellular determinants of target-site selection

5 July 2018

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SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope

5 July 2018

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Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila

5 July 2018

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A role for LEDGF/p75 in targeting HIV DNA integration

5 July 2018

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Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity

5 July 2018

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Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription.

5 July 2018

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Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites

5 July 2018

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Gene recruitment of the activated INO1 locus to the nuclear membrane

5 July 2018

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Active genes dynamically colocalize to shared sites of ongoing transcription

5 July 2018

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Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

5 July 2018

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LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

5 July 2018

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Role of Nup98 in nuclear entry of human immunodeficiency virus type 1 cDNA.

5 July 2018

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Capsid is a dominant determinant of retrovirus infectivity in nondividing cells

5 July 2018

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Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization

5 July 2018

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Human immunodeficiency virus type 1 DNA nuclear import and integration are mitosis independent in cycling cells

5 July 2018

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Transcription start regions in the human genome are favored targets for MLV integration

5 July 2018

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LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

5 July 2018

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HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

5 July 2018

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HIV-1 integration in the human genome favors active genes and local hotspots

5 July 2018

1 reference

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Initial sequencing and analysis of the human genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

The Sequence of the Human Genome

5 July 2018

1 reference

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A human importin-beta family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

Chromosome structure and human immunodeficiency virus type 1 cDNA integration: centromeric alphoid repeats are a disfavored target

5 July 2018

1 reference

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In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

5 July 2018

1 reference

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Nonrandom gene organization: structural arrangements of specific pre-mRNA transcription and splicing with SC-35 domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

Integration of murine leukemia virus DNA depends on mitosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

DNase I-hypersensitive sites are associated with both long terminal repeats and with the intragenic enhancer of integrated human immunodeficiency virus type 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

Retroviral integration into minichromosomes in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053352

Transportin-SR2 imports HIV into the nucleus

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001313

Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001313

HIV integration site selection: targeting in macrophages and the effects of different routes of viral entry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001313

Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001313

Nuclear pore association confers optimal expression levels for an inducible yeast gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001313

The influence of DNA and nucleosome structure on integration events directed by HIV integrase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21423673

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genome-scale RNAi screen for host factors required for HIV replication

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21423673

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PPAT.1001313

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21423673%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21423673%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

21423673

1 reference