Ligand-specific conformation of extracellular loop-2 in the angiotensin II type 1 receptor (Q33855316)

29 July 2017

Ligand-specific conformation of extracellular loop-2 in the angiotensin II type 1 receptor (English)

1 reference

29 July 2017

Hamiyet Unal

1

1 reference

29 July 2017

Rajaganapathi Jagannathan

series ordinal

2

1 reference

29 July 2017

Manjunatha B Bhat

series ordinal

3

1 reference

29 July 2017

Sadashiva S Karnik

series ordinal

4

1 reference

29 July 2017

language of work or name

English

0 references

publication date

18 March 2010

1 reference

Journal of Biological Chemistry

29 July 2017

1 reference

29 July 2017

285

1 reference

29 July 2017

21

1 reference

29 July 2017

16341-16350

1 reference

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

The structure and function of G-protein-coupled receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Structure of a beta1-adrenergic G-protein-coupled receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Crystal structure of the ligand-free G-protein-coupled receptor opsin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Structural diversity of G protein-coupled receptors and significance for drug discovery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Scalable molecular dynamics with NAMD

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Determining the environment of the ligand binding pocket of the human angiotensin II type I (hAT1) receptor using the methionine proximity assay.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Essential role for the second extracellular loop in C5a receptor activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

VEGA – An open platform to develop chemo-bio-informatics applications, using plug-in architecture and script programming

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Activation of G-protein-coupled receptors: a common molecular mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Constitutive activation of the angiotensin II type 1 receptor alters the spatial proximity of transmembrane 7 to the ligand-binding pocket

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

TM2-TM7 interaction in coupling movement of transmembrane helices to activation of the angiotensin II type-1 receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Autoantibodies against AT1-receptor and alpha1-adrenergic receptor in patients with hypertension

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Stimulatory activity of anti-peptide antibodies against the second extracellular loop of human M2 muscarinic receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Crystal structure of rhodopsin: A G protein-coupled receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Systematic identification of mutations that constitutively activate the angiotensin II type 1A receptor by screening a randomly mutated cDNA library with an original pharmacological bioassay

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Mechanism of constitutive activation of the AT1 receptor: influence of the size of the agonist switch binding residue Asn(111).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

G protein-coupled receptors. I. Diversity of receptor-ligand interactions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

An agonist-like monoclonal antibody against the human beta2-adrenoceptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Angiotensin II receptors and angiotensin II receptor antagonists.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Differential structural requirements for specific binding of nonpeptide and peptide antagonists to the AT1 angiotensin receptor. Identification of amino acid residues that determine binding of the antihypertensive drug losartan.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Conformational analysis of two cyclic analogs of angiotensin: implications for the biologically active conformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Differentiation between binding sites for angiotensin II and nonpeptide antagonists on the angiotensin II type 1 receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Disulfide bridges in extracellular domains of angiotensin II receptor type IA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Interaction of Phe8 of angiotensin II with Lys199 and His256 of AT1 receptor in agonist activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Acetylcholine receptor channel structure probed in cysteine-substitution mutants.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871501

Structure. Rhodopsin sees the light

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094870

Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094870

Constitutive activation of angiotensin II type 1 receptor alters the orientation of transmembrane Helix-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094870

Reversible inactivation of AT(2) angiotensin II receptor from cysteine-disulfide bond exchange.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094870

Residues 293 and 294 are ligand contact points of the human angiotensin type 1 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094870

Molecular characterization of a purified 5-HT4 receptor: a structural basis for drug efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094870

Three-dimensional structure of an angiotensin II-Fab complex at 3 A: hormone recognition by an anti-idiotypic antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094870

Identification of critical extracellular loop residues involved in alpha 1-adrenergic receptor subtype-selective antagonist binding

21 January 2018

1 reference

12 December 2020

Candesartan (CV-11974) dissociates slowly from the angiotensin AT1 receptor

1 reference

12 December 2020

Constitutive activation of the TSH receptor by spontaneous mutations affecting the N-terminal extracellular domain

1 reference

12 December 2020

Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 receptor

1 reference

12 December 2020

Determination of peptide contact points in the human angiotensin II type I receptor (AT1) with photosensitive analogs of angiotensin II

1 reference

12 December 2020

The second extracellular loop: a damper for G protein-coupled receptors?

1 reference

12 December 2020

Specific nonpeptide photoprobes as tools for the structural study of the angiotensin II AT(1) receptor

1 reference

12 December 2020

Photolabeling identifies position 172 of the human AT(1) receptor as a ligand contact point: receptor-bound angiotensin II adopts an extended structure

1 reference

12 December 2020

Identification of amino acid residues of rat angiotensin II receptor for ligand binding by site directed mutagenesis

1 reference

12 December 2020

Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms

1 reference

12 December 2020

The docking of Arg2 of angiotensin II with Asp281 of AT1 receptor is essential for full agonism

1 reference

12 December 2020

Mutagenesis and the molecular modeling of the rat angiotensin II receptor (AT1)

1 reference

12 December 2020

Manifold active-state conformations in GPCRs: agonist-activated constitutively active mutant AT1 receptor preferentially couples to Gq compared to the wild-type AT1 receptor

1 reference

12 December 2020

Activation of the angiotensin II type 1 receptor leads to movement of the sixth transmembrane domain: analysis by the substituted cysteine accessibility method

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.094870

1 reference

29 July 2017

1 reference

29 July 2017

1 reference