Bacterial proteinases as targets for the development of second-generation antibiotics (Q33857438)

29 July 2017

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title

Bacterial proteinases as targets for the development of second-generation antibiotics (English)

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29 July 2017

2

J Potempa

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29 July 2017

J Travis

1

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29 July 2017

language of work or name

English

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publication date

1 March 2000

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Biochimica et Biophysica Acta

29 July 2017

published in

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29 July 2017

volume

1477

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29 July 2017

issue

1-2

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29 July 2017

page(s)

35-50

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The HIV protease and therapies for AIDS.

29 July 2017

cites work

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HIV-protease inhibitors

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7 January 2021

Peptides and micro-organisms

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7 January 2021

Are bacterial proteinases pathogenic factors?

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7 January 2021

Role of microbial proteases in pathogenesis

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7 January 2021

Human plasma proteinase inhibitors

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7 January 2021

Porphyromonas gingivalis: a proteinase/gene accounting audit

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7 January 2021

Probing serpin reactive-loop conformations by proteolytic cleavage

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Interstitial collagenase (matrix metalloproteinase-1) expresses serpinase activity

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Inactivation of human plasma alpha 1-proteinase inhibitor by human PMN leucocyte collagenase

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Cleavage and inactivation of alpha 1-antitrypsin by metalloproteinases released from neutrophils

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Purification and characterization of a novel cysteine proteinase (periodontain) from Porphyromonas gingivalis. Evidence for a role in the inactivation of human alpha1-proteinase inhibitor

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

The house dust mite allergen Der p1 catalytically inactivates alpha 1-antitrypsin by specific reactive centre loop cleavage: a mechanism that promotes airway inflammation and asthma

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Proteolysis of human native and oxidised α1-proteinase inhibitor by matrulysin and stromelysin

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Proteolytic inactivation of human α1 antitrypsin by human stromelysin

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7 January 2021

Inactivation of human plasma alpha 1-proteinase inhibitor by a metalloproteinase from Serratia marcescens

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Purification and characterization of a novel endopeptidase in ragweed (Ambrosia artemisiifolia) pollen

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Interactions of α-1-Antichymotrypsin, α-1-Proteinase Inhibitor, and α-2-Macroglobulin with the Fungal Enzyme, Seaprose

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Enzymatic inactivation of human antithrombin III. Limited proteolysis of the inhibitor by snake venom proteinases in the presence of heparin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Plakalbumin, alpha 1-antitrypsin, antithrombin and the mechanism of inflammatory thrombosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Mobile reactive centre of serpins and the control of thrombosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

The structural basis for neutrophil inactivation of C1 inhibitor.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Inactivation of human plasma C1-inhibitor by human PMN leucocyte matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed, and reactive site cleaved serpins: comparison of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, antithrombin III, alpha 2-antiplasmi

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

The primary elastase inhibitor (elastasin) and trypsin inhibitor (contrapsin) in the goat are serpins related to human alpha 1-anti-chymotrypsin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Comparative properties of two cysteine proteinases (gingipains R), the products of two related but individual genes of Porphyromonas gingivalis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

The role of proteolytic enzymes in the development of pulmonary emphysema and periodontal disease

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Activation of human matrix metalloproteinases by various bacterial proteinases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Human matrix metalloprotease activation by insults of bacterial infection involving proteases and free radicals

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Activation and novel processing of matrix metalloproteinases by a thiol-proteinase from the oral anaerobe Porphyromonas gingivalis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Capturing host plasmin(ogen): a common mechanism for invasive pathogens?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Production of chemotactic factors for neutrophils following the interaction of Bacteroides gingivalis with purified C5

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

The effect of periodontal proteolytic Bacteroides species on proteins of the human complement system

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

The role of complement in periodontal diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Collagenases (first of three parts).

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

The IgA1 proteases of pathogenic bacteria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Biological significance of IgA1 proteases in bacterial colonization and pathogenesis: critical evaluation of experimental evidence

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

The cleavage of immunoglobulin G in vitro and in vivo by a proteinase secreted by the urinary tract pathogen Proteus mirabilis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

A proteolytic enzyme secreted by Proteus mirabilis degrades immunoglobulins of the immunoglobulin A1 (IgA1), IgA2, and IgG isotypes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Degradation of plasma proteins by the trypsin-like enzyme of Porphyromonas gingivalis and inhibition of protease activity by a serine protease inhibitor of human plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Cleavage of human immunoglobulins by serine proteinase from Staphylococcus aureus

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Characterization of immunoglobulin G-degrading proteases of Prevotella intermedia and Prevotella nigrescens

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Pathogenesis of periodontitis: a major arginine-specific cysteine proteinase from Porphyromonas gingivalis induces vascular permeability enhancement through activation of the kallikrein/kinin pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

A serratial protease causes vascular permeability reaction by activation of the Hageman factor-dependent pathway in guinea pigs

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Activation of bradykinin generating cascade by Vibrio cholerae protease.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Streptococcal cysteine proteinase releases kinins: a virulence mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Involvement of bradykinin generation in intravascular dissemination of Vibrio vulnificus and prevention of invasion by a bradykinin antagonist.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Bradykinin generation triggered by Pseudomonas proteases facilitates invasion of the systemic circulation by Pseudomonas aeruginosa

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Effect of Pseudomonas aeruginosa elastase and alkaline protease on serum complement and isolated components C1q and C3

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Elastase of Pseudomonas aeruginosa: inactivation of complement components and complement-derived chemotactic and phagocytic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Degradation of human immunoglobulins G and M and complement factors C3 and C5 by black-pigmented Bacteroides

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Activation of blood clotting factors by microbial proteinases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Activation of protein C by arginine-specific cysteine proteinases (gingipains-R) from Porphyromonas gingivalis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Activation of blood coagulation factor X by arginine-specific cysteine proteinases (gingipain-Rs) from Porphyromonas gingivalis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Oral pathogens: from dental plaque to cardiac disease

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

The pathobiology of periodontal diseases may affect systemic diseases: inversion of a paradigm.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Purification and characterisation of a plasminogen-binding protein from Haemophilus influenzae. Sequence determination reveals identity with aspartase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Receptors for human plasminogen on gram-negative bacteria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Binding of plasminogen to Neisseria meningitidis and Neisseria gonorrhoeae and formation of surface-associated plasmin.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Binding and activation of plasminogen at the surface of Staphylococcus aureus. Increase in affinity after conversion to the Lys form of the ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Selective distribution of a high-affinity plasminogen-binding site among group A streptococci associated with impetigo

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Surface bound plasmin promotes migration of Streptococcus pneumoniae through reconstituted basement membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Interaction of a group A Streptococcus within human plasma results in assembly of a surface plasminogen activator that contributes to occupancy of surface plasmin-binding structures

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Activation of plasminogen to plasmin by a protease associated with the outer membrane of Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Omptin: an Escherichia coli outer membrane proteinase that activates plasminogen.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

A surface protease and the invasive character of plague

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Effect of free and vesicle-bound cysteine proteinases of Porphyromonas gingivalis on plasma clot formation: implications for bleeding tendency at periodontitis sites

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Characterization of the binding activities of proteinase-adhesin complexes from Porphyromonas gingivalis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Characterization and purification of an outer membrane metalloproteinase from Pseudomonas aeruginosa with fibrinogenolytic activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Pseudomonas aeruginosa alkaline proteinase might share a biological function with plasmin.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Protease IV, a unique extracellular protease and virulence factor from Pseudomonas aeruginosa

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Legionella pneumophila protease inactivates interleukin-2 and cleaves CD4 on human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Inactivation of human gamma interferon by Pseudomonas aeruginosa proteases: elastase augments the effects of alkaline protease despite the presence of alpha 2-macroglobulin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Inactivation of tumor necrosis factor-alpha by proteinases (gingipains) from the periodontal pathogen, Porphyromonas gingivalis. Implications of immune evasion

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Cytokine degradation by biofilms of Porphyromonas gingivalis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Interactions between periodontopathogenic bacteria and cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Rapid and efficient inactivation of IL-6 gingipains, lysine- and arginine-specific proteinases from Porphyromonas gingivalis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Modulation of interleukin-8 activity by gingipains from Porphyromonas gingivalis: implications for pathogenicity of periodontal disease

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Interleukin-8 processing by neutrophil elastase, cathepsin G and proteinase-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

IL-8 degradation by Porphyromonas gingivalis proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Novel pathogenic mechanism of microbial metalloproteinases: liberation of membrane-anchored molecules in biologically active form exemplified by studies with the human interleukin-6 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Role of Staphylococcus protease in the development of influenza pneumonia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Synergistic role of staphylococcal proteases in the induction of influenza virus pathogenicity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Interactions between bacteria and influenza A virus in the development of influenza pneumonia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Advances in the pathogenesis of periodontitis: summary of developments, clinical implications and future directions

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

The microbial challenge in periodontitis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Role of bacterial proteinases in matrix destruction and modulation of host responses

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Adhere today, here tomorrow: oral bacterial adherence

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Porphyromonas gingivalis trypsin-like protease: a possible natural ligand for the neutrophil formyl peptide receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

Dependence of vascular permeability enhancement on cysteine proteinases in vesicles of Porphyromonas gingivalis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900278-2

7 January 2021

10.1016/S0167-4838(99)00278-2

Identifiers

DOI

1 reference

29 July 2017

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