DNA breaks and chromosomal aberrations arise when replication meets base excision repair (Q33859100)

29 July 2017

title

DNA breaks and chromosomal aberrations arise when replication meets base excision repair (English)

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29 July 2017

4

Teodora Nikolova

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29 July 2017

Michael Ensminger

1

1 reference

29 July 2017

Lucie Iloff

2

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29 July 2017

Christian Ebel

3

1 reference

29 July 2017

Bernd Kaina

5

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29 July 2017

Markus Lӧbrich

6

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29 July 2017

language of work or name

English

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publication date

30 June 2014

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29 July 2017

number of pages

15

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inferred from page(s)

published in

Journal of Cell Biology

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29 July 2017

volume

206

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29 July 2017

issue

1

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29 July 2017

page(s)

29-43

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4085701/fullTextXML

inferred from PubMed Central ID database lookup

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Co-ordination of base excision repair and genome stability

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

5 July 2018

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A chemical and genetic approach together define the biological consequences of 3-methyladenine lesions in the mammalian genome

5 July 2018

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5 July 2018

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Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

5 July 2018

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XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro

5 July 2018

1 reference

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Requirement of mammalian DNA polymerase-beta in base-excision repair.

5 July 2018

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Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

5 July 2018

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A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange

5 July 2018

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Mechanisms of chromosomal aberration production. 3. Chemicals and ionizing radiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085701

Incorporated bromodeoxyuridine enhances the sister-chromatid exchange and chromosomal aberration frequencies in an EMS-sensitive Chinese hamster cell line

5 July 2018

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Negative regulatory element associated with potentially functional promoter and enhancer elements in the long terminal repeats of endogenous murine leukemia virus-related proviral sequences.

5 July 2018

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Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085701

Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase

5 July 2018

1 reference

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A Chinese hamster ovary cell mutant (EM-C11) with sensitivity to simple alkylating agents and a very high level of sister chromatid exchanges

5 July 2018

1 reference

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Mutagen specificity in the induction of chromosomal aberrations in somatic cells of Drosophila melanogaster

5 July 2018

1 reference

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Chromosome damage in the bone marrow of mice treated with the methylating agents methyl methanesulphonate and N-methyl-N-nitrosourea in the presence or absence of caffeine, and its relationship with thymoma induction

5 July 2018

1 reference

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Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085701

The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085701

Study of interaction of XRCC1 with DNA and proteins of base excision repair by photoaffinity labeling technique.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085701

XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085701

Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085701

Nuclear retention of ATM at sites of DNA double strand breaks

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085701

Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085701

Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085701

The induction of chromosome aberrations by nitrogen mustard and its dependence on DNA synthesis

29 October 2018

1 reference

12 December 2020

Induction of sister-chromatid exchanges (SCEs) and chromosomal aberrations by mitomycin C and methyl methanesulfonate in Chinese hamster ovary cells. An evaluation of methodology for detection of SCEs and of persistent DNA lesions towards the freque

1 reference

12 December 2020

Molecular mechanisms involved in the production of chromosomal aberrations. III. Restriction endonucleases

1 reference

12 December 2020

Methylation-induced blocks to in vitro DNA replication

1 reference

12 December 2020

Induction of sister-chromatid exchanges by restriction endonucleases

1 reference

12 December 2020

Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis

1 reference

12 December 2020

Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents--a case of imbalanced DNA repair

1 reference

12 December 2020

Critical steps in alkylation-induced aberration formation

1 reference

12 December 2020

Single cell gel electrophoresis: detection of DNA damage at different levels of sensitivity

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12 December 2020

Identifiers

DOI

10.1083/JCB.201312078

1 reference

29 July 2017

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29 July 2017

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