Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease (Q33862071)

29 July 2017

title

Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease (English)

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29 July 2017

0 references

1 reference

2

David S Miller

1 reference

29 July 2017

Anika M S Hartz

1

1 reference

29 July 2017

Björn Bauer

series ordinal

3

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29 July 2017

publication date

25 January 2010

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29 July 2017

published in

Molecular Pharmacology

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29 July 2017

volume

77

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29 July 2017

issue

5

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29 July 2017

page(s)

715-723

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ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides.

29 July 2017

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P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-beta

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5 July 2018

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5 July 2018

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P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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GLUT-1 expression in the cerebra of patients with Alzheimer's disease

5 July 2018

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Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833

5 July 2018

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5 July 2018

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P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

5 July 2018

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5 July 2018

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Amyloid beta deposition is related to decreased glucose transporter-1 levels and hippocampal atrophy in brains of aged APP/PS1 mice

5 July 2018

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MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier

29 October 2018

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RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease

29 October 2018

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In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation

29 October 2018

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Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872973

Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872973

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872973

Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872973

RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20101004

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20101004

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/MOL.109.061754

1 reference

29 July 2017

1 reference

29 July 2017

1 reference