Combining CD19 redirection and alloanergization to generate tumor-specific human T cells for allogeneic cell therapy of B-cell malignancies. (Q33862876)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424114%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Combining CD19 redirection and alloanergization to generate tumor-specific human T cells for allogeneic cell therapy of B-cell malignancies (English)

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1 February 2020

5

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1 February 2020

3

Helen Huls

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1 February 2020

7

Richard E Champlin

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1 February 2020

8

Lee M Nadler

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1 February 2020

author name string

Jeff K Davies

1

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1 February 2020

Harjeet Singh

2

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1 February 2020

Dongin Yuk

4

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1 February 2020

Partow Kebriaei

6

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1 February 2020

Eva C Guinan

9

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1 February 2020

Laurence J N Cooper

10

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language of work or name

English

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publication date

27 April 2010

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1 February 2020

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1 February 2020

volume

70

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1 February 2020

issue

10

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1 February 2020

page(s)

3915-3924

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Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity.

1 February 2020

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1 reference

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Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

5 July 2018

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Induction of alloanergy in human donor T cells without loss of pathogen or tumor immunity

5 July 2018

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Twenty years of unrelated donor bone marrow transplantation for pediatric acute leukemia facilitated by the National Marrow Donor Program

5 July 2018

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Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of 2 phase 1 studies

5 July 2018

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Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells

5 July 2018

1 reference

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Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system

5 July 2018

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Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies

5 July 2018

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Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates

5 July 2018

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A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

5 July 2018

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Epstein Barr virus specific cytotoxic T lymphocytes expressing the anti-CD30zeta artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease

5 July 2018

1 reference

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A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

5 July 2018

1 reference

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Differentiation of naive cord-blood T cells into CD19-specific cytolytic effectors for posttransplantation adoptive immunotherapy

5 July 2018

1 reference

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Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy.

5 July 2018

1 reference

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Accelerated telomere shortening in response to life stress

5 July 2018

1 reference

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Enhanced antilymphoma efficacy of CD19-redirected influenza MP1-specific CTLs by cotransfer of T cells modified to present influenza MP1.

5 July 2018

1 reference

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Human CD62L- memory T cells are less responsive to alloantigen stimulation than CD62L+ naive T cells: potential for adoptive immunotherapy and allodepletion.

5 July 2018

1 reference

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Central memory and effector memory T cell subsets: function, generation, and maintenance

5 July 2018

1 reference

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Adoptive cellular therapy for early cytomegalovirus infection after allogeneic stem-cell transplantation with virus-specific T-cell lines.

5 July 2018

1 reference

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Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses

5 July 2018

1 reference

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Targeting tumours with genetically enhanced T lymphocytes

5 July 2018

1 reference

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Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors

5 July 2018

1 reference

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Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation

5 July 2018

1 reference

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Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1

5 July 2018

1 reference

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Specific elimination of alloreactive T cells by an anti-interleukin-2 receptor B chain-specific immunotoxin

5 July 2018

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Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo

5 July 2018

1 reference

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CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells.

29 October 2018

1 reference

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Characterization of an artificial antigen-presenting cell to propagate cytolytic CD19-specific T cells.

29 October 2018

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Serious infections after unrelated donor transplantation in 136 children: impact of stem cell source

29 October 2018

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Leukemic stem cells in childhood high-risk ALL/t(9;22) and t(4;11) are present in primitive lymphoid-restricted CD34+CD19- cells.

29 October 2018

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Outcome of allogeneic hematopoietic stem-cell transplantation in adult patients with acute lymphoblastic leukemia: no difference in related compared with unrelated transplant in first complete remission

29 October 2018

1 reference

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Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15.

29 October 2018

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A comparison of allogeneic and autologous bone marrow transplantation for lymphoblastic lymphoma

29 October 2018

1 reference

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Dual-specific T cells combine proliferation and antitumor activity

29 October 2018

1 reference

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T-cell clones can be rendered specific for CD19: toward the selective augmentation of the graft-versus-B-lineage leukemia effect

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2873153

Transplantation of anergic histoincompatible bone marrow allografts

29 October 2018

1 reference

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Complete blockade of B7 family-mediated costimulation is necessary to induce human alloantigen-specific anergy: a method to ameliorate graft-versus-host disease and extend the donor pool

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2873153

High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: potential role of Campath-1H in delaying immune reconstitution

29 October 2018

1 reference

12 December 2020

Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma

1 reference

12 December 2020

Ex vivo depletion of alloreactive cells based on CFSE dye dilution, activation antigen selection, and dendritic cell stimulation

1 reference

12 December 2020

Differentiation of Human Alloreactive CD4+ and CD8+ T Cells In Vitro

1 reference

12 December 2020

Characterization of acute lymphoblastic leukemia progenitor cells

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12 December 2020

B4, a human B lymphocyte-associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes

1 reference

12 December 2020

Immune reconstitution following bone marrow transplantation: comparison of recipients of T-cell depleted marrow with recipients of conventional marrow grafts

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12 December 2020

Shortened telomeres in clonally expanded CD28-CD8+ T cells imply a replicative history that is distinct from their CD28+CD8+ counterparts

1 reference

12 December 2020

Sleeping beauty vector system moves toward human trials in the United States

1 reference

12 December 2020

Functional assessment and specific depletion of alloreactive human T cells using flow cytometry

1 reference

12 December 2020

Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience

1 reference

12 December 2020

10.1158/0008-5472.CAN-09-3845

Identifiers

DOI

1 reference

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1 February 2020

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1 February 2020

PubMed publication ID

20424114

1 reference