A critical role of helix 3-helix 5 interaction in steroid hormone receptor function (Q33864134)

29 July 2017

A critical role of helix 3-helix 5 interaction in steroid hormone receptor function (English)

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29 July 2017

Junhui Zhang

1

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29 July 2017

Jessica Simisky

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2

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29 July 2017

Francis T F Tsai

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3

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29 July 2017

David S Geller

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4

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29 July 2017

language of work or name

English

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publication date

14 February 2005

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

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29 July 2017

102

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29 July 2017

8

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29 July 2017

2707-2712

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Binding of ligands and activation of transcription by nuclear receptors.

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

Antagonism in the human mineralocorticoid receptor.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

Atomic structure of progesterone complexed with its receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

Molecular basis of agonism and antagonism in the oestrogen receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

Constitutively active human estrogen receptors containing amino acid substitutions for tyrosine 537 in the receptor protein.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

Hormone binding domain of human glucocorticoid receptor. Enhancement of transactivation function by substitution mutants M565R and A573Q.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

Cysteines 638 and 665 in the hormone binding domain of human glucocorticoid receptor define the specificity to glucocorticoids

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

Creation of "super" glucocorticoid receptors by point mutations in the steroid binding domain.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

A single amino acid that determines the sensitivity of progesterone receptors to RU486.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549476

The nuclear receptor ligand-binding domain: structure and function.

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409663102

Homology modelling of the ligand-binding domain of glucocorticoid receptor: binding site interactions with cortisol and corticosterone

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409663102

Functional probing of the human glucocorticoid receptor steroid-interacting surface by site-directed mutagenesis. Gln-642 plays an important role in steroid recognition and binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409663102

Homology modeling using multiple molecular dynamics simulations and docking studies of the human androgen receptor ligand binding domain bound to testosterone and nonsteroidal ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409663102

Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409663102

Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409663102

Molecular basis for the constitutive activity of estrogen-related receptor alpha-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409663102

Specific recognition of androgens by their nuclear receptor. A structure-function study

21 January 2018

1 reference

12 December 2020

The pure antiestrogen ICI 182,780 inhibits progestin-induced transcription

1 reference

12 December 2020

Valine 571 functions as a regional organizer in programming the glucocorticoid receptor for differential binding of glucocorticoids and mineralocorticoids

1 reference

12 December 2020

Sequences in the ligand-binding domains of the human androgen and progesterone receptors which determine their distinct ligand identities

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0409663102

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29 July 2017

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29 July 2017

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