Cholesterol detoxification by the nuclear pregnane X receptor (Q33864257)

29 July 2017

title

Cholesterol detoxification by the nuclear pregnane X receptor (English)

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29 July 2017

Steven A Kliewer

1

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29 July 2017

language of work or name

English

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publication date

14 February 2005

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

102

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29 July 2017

issue

8

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29 July 2017

page(s)

2675-2676

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Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

The nuclear receptor PXR: a master regulator of "homeland" defense

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

Metabolism of 4 beta -hydroxycholesterol in humans.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

Orphan nuclear receptors: the exotics of xenobiotics.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

Mechanisms of cholestasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

Biliary flow after microsomal enzyme induction.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

Comparison of rifampicin with phenobarbitone for treatment of pruritus in biliary cirrhosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549480

CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0500159102

Induction of CYP3A by 2,3-oxidosqualene:lanosterol cyclase inhibitors is mediated by an endogenous squalene metabolite in primary cultured rat hepatocytes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0500159102

Alteration of the degree of biliary cholesterol saturation in the hamster and rat by manipulation of the pools of preformed and newly synthesized cholesterol

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15710871

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0500159102

1 reference

29 July 2017

0 references

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29 July 2017

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