Structural requirements of the major protective antibody to Haemophilus influenzae type b (Q33867521)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10225914%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

title

Structural requirements of the major protective antibody to Haemophilus influenzae type b (English)

1 reference

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5 December 2019

main subject

Haemophilus influenzae

object named as

Haemophilus influenzae

1 reference

4

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5 December 2019

author name string

Hougs L

series ordinal

1

1 reference

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5 December 2019

Juul L

series ordinal

2

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5 December 2019

Svejgaard A

series ordinal

3

1 reference

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5 December 2019

language of work or name

English

0 references

publication date

1 May 1999

1 reference

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5 December 2019

published in

Infection and Immunity

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5 December 2019

volume

67

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5 December 2019

issue

5

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5 December 2019

page(s)

2503-2514

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10225914%20AND%20SRC:MED&resulttype=core&format=json

The first dose of a Haemophilus influenzae type b conjugate vaccine reactivates memory B cells: evidence for extensive clonal selection, intraclonal affinity maturation, and multiple isotype switches to IgA2.

5 December 2019

cites work

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Decreased frequency of rearrangement due to the synergistic effect of nucleotide changes in the heptamer and nonamer of the recombination signal sequence of the V kappa gene A2b, which is associated with increased susceptibility of Navajos to Haemop

5 July 2018

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The normally expressed kappa immunoglobulin light chain gene repertoire and somatic mutations studied by single-sided specific polymerase chain reaction (PCR); frequent occurrence of features often assigned to autoimmunity

5 July 2018

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Human Fab fragments specific for the Haemophilus influenzae b polysaccharide isolated from a bacteriophage combinatorial library use variable region gene combinations and express an idiotype that mirrors in vivo expression

5 July 2018

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The progeny of a single virgin B cell predominates the human recall B cell response to the capsular polysaccharide of Haemophilus influenzae type b.

5 July 2018

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A defective Vkappa A2 allele in Navajos which may play a role in increased susceptibility to haemophilus influenzae type b disease

5 July 2018

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Variable region expression in the antibody responses of infants vaccinated with Haemophilus influenzae type b polysaccharide-protein conjugates. Description of a new lambda light chain-associated idiotype and the relation between idiotype expression

5 July 2018

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Predominant V-region gene configurations in the human antibody response to Haemophilus influenzae capsule polysaccharide

5 July 2018

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The immunoglobulin kappa locus of primates

5 July 2018

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Functional capacities of clonal antibodies to Haemophilus influenzae type b polysaccharide.

5 July 2018

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Phage-Display Libraries of Murine and Human Antibody Fab Fragments

5 July 2018

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Rheumatoid factors from the peripheral blood of two patients with rheumatoid arthritis are genetically heterogeneous and somatically mutated

5 July 2018

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Rapid analysis of rearranged kappa light chain genes of circulating polysaccharide-specific B lymphocytes by means of immunomagnetic beads and the polymerase chain reaction

5 July 2018

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Somatic mutation of human immunoglobulin V genes: bias, rate, and regulation.

5 July 2018

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Mutation drift and repertoire shift in the maturation of the immune response

5 July 2018

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Genetics of the phosphocholine-specific antibody response to Streptococcus pneumoniae. Germ-line but not mutated T15 antibodies are dominantly selected.

5 July 2018

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Model-building study of the combining sites of two antibodies to alpha (1----6)dextran

5 July 2018

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Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP

5 July 2018

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A rapid method for isolating high quality plasmid DNA suitable for DNA sequencing

5 July 2018

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5 July 2018

1 reference

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Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. IV. The less frequently expressed VL are heterogeneous.

5 July 2018

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Restricted Ig H chain V gene usage in the human antibody response to Haemophilus influenzae type b capsular polysaccharide

5 July 2018

1 reference

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An idiotypic marker associated with a germ-line encoded kappa light chain variable region that predominates the vaccine-induced human antibody response to the Haemophilus influenzae b polysaccharide

5 July 2018

1 reference

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Distinct pattern of antibody reactivity with oligomeric or polymeric forms of the capsular polysaccharide of Haemophilus influenzae type b

5 July 2018

1 reference

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Immunoglobulin light chain variable region gene sequences for human antibodies to Haemophilus influenzae type b capsular polysaccharide are dominated by a limited number of V kappa and V lambda segments and VJ combinations

5 July 2018

1 reference

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Structural repertoire of the human VH segments

5 July 2018

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The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops

5 July 2018

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The human antibody V region repertoire to the type B capsular polysaccharide of Haemophilus influenzae

5 July 2018

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Capsular polymer of Haemophilus influenzae, type b. I. Structural characterization of the capsular polymer of strain Eagan

5 July 2018

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5 July 2018

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ABGEN: a knowledge-based automated approach for antibody structure modeling

5 July 2018

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Functional expression of the IGKV A18b gene and its idiotypic cross-reactivity with the A2 variable region

29 October 2018

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New alleles of IGKV genes A2 and A18 suggest significant human IGKV locus polymorphism

29 October 2018

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Diversity of immunoglobulin light chain usage in the human immune response to Haemophilus influenzae type b capsular polysaccharide.

29 October 2018

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Induction of immunologic memory in infants primed with Haemophilus influenzae type b conjugate vaccines.

29 October 2018

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Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction

29 October 2018

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Extensive allelic sequence variation in the J region of the human immunoglobulin heavy chain gene locus.

29 October 2018

1 reference

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Identical VHD and DJH junctions in monoclonal antibodies derived in response to dextran B512 could be the result of developmental selection

29 October 2018

1 reference

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Cross-reactivity with Escherichia coli K100 in the human serum anticapsular antibody response to Haemophilus influenzae type B.

29 October 2018

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Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

29 October 2018

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12 December 2020

Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. III. A single VKII gene and one of several JK genes are joined by an invariant arginine to form the most common L chain V region

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12 December 2020

Population studies of the human VK A18 gene polymorphism in Caucasians, blacks and Eskimos

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12 December 2020

Age-dependent V region expression in the human antibody response to the Haemophilus influenzae type b polysaccharide

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12 December 2020

The immunoglobulin kappa locus: polymorphism and haplotypes of Caucasoid and non-Caucasoid individuals

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12 December 2020

Restricted immunoglobulin VH usage and VDJ combinations in the human response to Haemophilus influenzae type b capsular polysaccharide. Nucleotide sequences of monospecific anti-Haemophilus antibodies and polyspecific antibodies cross-reacting with

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12 December 2020

Modeling study of antibody combining sites to (alpha 1-6)dextrans. Predictions of the conformational contribution of VL-CDR3 and J kappa segments to groove-type combining sites

1 reference

12 December 2020

Functional differences in idiotypically defined IgG1 anti-polysaccharide antibodies elicited by vaccination with Haemophilus influenzae type B polysaccharide-protein conjugates

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12 December 2020