AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation (Q33874358)

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English	AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation	scientific article

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation (English)

1 reference

Europe PubMed Central

29 July 2017

phosphorylation

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based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

tuberous sclerosis 2

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based on heuristic

inferred from title

tuberous sclerosis 2

1 reference

based on heuristic

inferred from title

author name string

Junyu Ning

1

1 reference

Europe PubMed Central

29 July 2017

David R Clemmons

2

1 reference

Europe PubMed Central

29 July 2017

publication date

2 April 2010

1 reference

Europe PubMed Central

29 July 2017

Molecular Endocrinology

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Europe PubMed Central

29 July 2017

24

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Europe PubMed Central

29 July 2017

1218-1229

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Europe PubMed Central

29 July 2017

6

1 reference

Europe PubMed Central

29 July 2017

Regulation of tissue growth through nutrient sensing

1 reference

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Treatment with TNF-alpha and IFN-gamma alters the activation of SER/THR protein kinases and the metabolic response to IGF-I in mouse c2c12 myogenic cells.

1 reference

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AMP-activated protein kinase mediates the interferon-gamma-induced decrease in intestinal epithelial barrier function

1 reference

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1 reference

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p66shc negatively regulates insulin-like growth factor I signal transduction via inhibition of p52shc binding to Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 leading to impaired growth factor receptor-bound protein-2 mem

1 reference

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The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

1 reference

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AMP-activated protein kinase mediates glucocorticoid-induced metabolic changes: a novel mechanism in Cushing's syndrome

1 reference

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Modifying IGF1 activity: an approach to treat endocrine disorders, atherosclerosis and cancer

1 reference

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Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794.

1 reference

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Angiotensin II stimulates transcription of insulin-like growth factor I receptor in vascular smooth muscle cells: role of nuclear factor-kappaB.

1 reference

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Skeletal muscle hypertrophy and atrophy signaling pathways

1 reference

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Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells

1 reference

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Activation of AMP-activated protein kinase (AMPK) inhibits protein synthesis: a potential strategy to prevent the development of cardiac hypertrophy

1 reference

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Dysregulation of the TSC-mTOR pathway in human disease

1 reference

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Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway

1 reference

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TSC2: filling the GAP in the mTOR signaling pathway

1 reference

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The AMP-activated protein kinase cascade--a unifying system for energy control

1 reference

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5 July 2018

TSC2 mediates cellular energy response to control cell growth and survival

1 reference

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Altered insulin-like growth factor-1 and nitric oxide sensitivities in hypertension contribute to vascular hyperplasia

1 reference

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5 July 2018

Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2

1 reference

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Akt regulates growth by directly phosphorylating Tsc2

1 reference

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

1 reference

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5 July 2018

Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1- and epidermal growth factor-dependent extracellular signal-regulated kinase pathway

1 reference

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Smooth muscle-targeted overexpression of insulin-like growth factor I results in enhanced vascular contractility

1 reference

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Dexamethasone inhibits insulin-like growth factor signaling and potentiates myoblast apoptosis

1 reference

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The insulin-like growth factor axis: A review of atherosclerosis and restenosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875806

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The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875806

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Blocking ligand occupancy of the alphaVbeta3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875806

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Insulin-like growth factors require phosphatidylinositol 3-kinase to signal myogenesis: dominant negative p85 expression blocks differentiation of L6E9 muscle cells

1 reference

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Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase

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The pathogenesis of atherosclerosis: a perspective for the 1990s

1 reference

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Berberine inhibits platelet-derived growth factor-induced growth and migration partly through an AMPK-dependent pathway in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875806

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AMPK activation inhibits the expression of HIF-1alpha induced by insulin and IGF-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875806

29 October 2018

Thiazolidinediones inhibit insulin-like growth factor-i-induced activation of p70S6 kinase and suppress insulin-like growth factor-I tumor-promoting activity.

1 reference

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Transactivation of the insulin-like growth factor-I receptor by angiotensin II mediates downstream signaling from the angiotensin II type 1 receptor to phosphatidylinositol 3-kinase

1 reference

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5'-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20363874

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based on heuristic

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Insulin-like growth factor (IGF)-binding proteins inhibit the smooth muscle cell migration responses to IGF-I and IGF-II

1 reference

https://pubmed.ncbi.nlm.nih.gov/20363874

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of hypoxia-inducible factor-1 through receptor tyrosine kinase transactivation in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20363874

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/ME.2009-0474

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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