Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth in vitro and in vivo (Q33875921)

29 July 2017

Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth in vitro and in vivo (English)

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29 July 2017

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Seung Joon Lee

1

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29 July 2017

Candice Krauthauser

2

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29 July 2017

Victoria Maduskuie

3

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29 July 2017

Paul T Fawcett

4

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29 July 2017

James M Olson

5

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29 July 2017

Sigrid A Rajasekaran

6

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29 July 2017

language of work or name

English

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publication date

18 April 2011

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29 July 2017

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29 July 2017

11

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29 July 2017

144

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https://scigraph.springernature.com/pub.10.1186/1471-2407-11-144

29 July 2017

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cites work

Curcumin (diferuloylmethane) induces apoptosis and blocks migration of human medulloblastoma cells

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Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts

5 July 2018

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Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation

5 July 2018

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Curcumin induces cell cycle arrest and apoptosis in human osteosarcoma (HOS) cells

5 July 2018

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Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells

5 July 2018

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Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

5 July 2018

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Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

5 July 2018

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Microtubule inhibitors: Differentiating tubulin-inhibiting agents based on mechanisms of action, clinical activity, and resistance

5 July 2018

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Curcumin blocks brain tumor formation

5 July 2018

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The many roles of histone deacetylases in development and physiology: implications for disease and therapy

5 July 2018

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Histone deacetylase inhibitors as novel anticancer therapeutics.

5 July 2018

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Pediatric medulloblastoma: toxicity of current treatment and potential role of protontherapy

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Childhood brain tumors: accomplishments and ongoing challenges

5 July 2018

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The epigenetics of cancer in children

5 July 2018

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Epigenetic changes in cancer

5 July 2018

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Acetylation of non-histone proteins modulates cellular signalling at multiple levels

5 July 2018

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Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Prostate-specific membrane antigen associates with anaphase-promoting complex and induces chromosomal instability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

HDAC4 inhibits cell-cycle progression and protects neurons from cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Curcumin and cancer: an "old-age" disease with an "age-old" solution

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Curcumin induces apoptosis in human neuroblastoma cells via inhibition of NFkappaB.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

The blood-brain barrier in health and chronic neurodegenerative disorders

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

The origins of medulloblastoma subtypes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Class IIa histone deacetylases: regulating the regulators

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Histone deacetylases: focus on the nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

The blood-brain barrier and cancer: transporters, treatment, and Trojan horses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Dietary antioxidant curcumin inhibits microtubule assembly through tubulin binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Anticancer activities of histone deacetylase inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Neuroprotection by histone deacetylase-related protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Acetylation and deacetylation of non-histone proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Clinical development of histone deacetylase inhibitors as anticancer agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Post-translational modifications regulate microtubule function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Histone deacetylases and cancer: causes and therapies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

5 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-144

Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-144

Neuronal apoptosis induced by histone deacetylase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-144

Constitutive repression of E2F1 transcriptional activity through HDAC proteins is essential for neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-144

Selective E2F-dependent gene transcription is controlled by histone deacetylase activity during neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-144

The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-144

Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-144

Curcumin induces apoptosis via inhibition of PI3'-kinase/AKT pathway in acute T cell leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-144

Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090367

29 October 2018

Identifiers

DOI

10.1186/1471-2407-11-144

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Dimensions Publication ID

29 July 2017

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1 reference

29 July 2017

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