Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation (Q39750898)

14 September 2017

Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation (English)

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14 September 2017

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14 September 2017

Emilia Maria Pedone

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Laura Antonucci

Laura Antonucci

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Enrico De Smaele

Enrico De Smaele

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Giuseppe Giannini

Gianluca Canettieri

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Lucia Di Marcotullio

Lucia Di Marcotullio

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author name string

Azzura Greco

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14 September 2017

Sonia Coni

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Paola Infante

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14 September 2017

Laura Pietrosanti

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Marianna Pelloni

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14 September 2017

Paola Gallinari

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14 September 2017

Alessandra Giorgi

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14 September 2017

Christian Steinkühler

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14 September 2017

Luigi Vitagliano

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14 September 2017

Carlo Pedone

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14 September 2017

M Eugenià Schinin

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14 September 2017

Isabella Screpanti

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14 September 2017

Alberto Gulino

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14 September 2017

17 January 2010

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132-142

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https://scigraph.springernature.com/pub.10.1038/ncb2013

14 September 2017

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cites work

The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB2013

Gli1 is important for medulloblastoma formation in Ptc1+/- mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB2013

Altered neural cell fates and medulloblastoma in mouse patched mutants

21 January 2018

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12 December 2020

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

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12 December 2020

A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

1 reference

12 December 2020

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

1 reference

12 December 2020

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

1 reference

12 December 2020

Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling

1 reference

12 December 2020

GLI activates transcription through a herpes simplex viral protein 16-like activation domain.

1 reference

12 December 2020

Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex

1 reference

12 December 2020

Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling.

1 reference

12 December 2020

The coactivator CRTC1 promotes cell proliferation and transformation via AP-1

1 reference

12 December 2020

Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family.

1 reference

12 December 2020

Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex

1 reference

12 December 2020

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

1 reference

12 December 2020

Negative regulation of the deacetylase SIRT1 by DBC1

1 reference

12 December 2020

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

1 reference

12 December 2020

Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice

1 reference

12 December 2020

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

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12 December 2020

The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein

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12 December 2020

Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases

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12 December 2020

Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells

1 reference

12 December 2020

Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3

1 reference

12 December 2020

Negative and positive regulation of gene expression by mouse histone deacetylase 1

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12 December 2020

Acetylation and deacetylation of non-histone proteins

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12 December 2020

Hedgehog antagonist REN(KCTD11) regulates proliferation and apoptosis of developing granule cell progenitors

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12 December 2020

Dual degradation signals control Gli protein stability and tumor formation

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12 December 2020

Hedgehog signaling in development and cancer.

1 reference

12 December 2020

Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development

1 reference

12 December 2020

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development

1 reference

12 December 2020

Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination.

1 reference

12 December 2020

Histone deacetylase 1 is required to repress Notch target gene expression during zebrafish neurogenesis and to maintain the production of motoneurones in response to hedgehog signalling

1 reference

12 December 2020

DBC1 is a negative regulator of SIRT1

1 reference

12 December 2020

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

1 reference

12 December 2020

Suberoylanilide hydroxamic acid is effective in preclinical studies of medulloblastoma.

1 reference

12 December 2020

Hedgehog signaling promotes medulloblastoma survival via Bc/II

1 reference

12 December 2020

SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response

1 reference

12 December 2020

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

1 reference

12 December 2020

Peptide mass fingerprinting using MALDI-TOF mass spectrometry

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12 December 2020

Small molecule modulation of Smoothened activity

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12 December 2020

Combined targeting of histone deacetylases and hedgehog signaling enhances cytoxicity in pancreatic cancer.

1 reference

12 December 2020

Hedgehog-Gli Signaling in Human Disease

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB2013

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCB2013

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Dimensions Publication ID

14 September 2017

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