Importance of protein dynamics during enzymatic C-H bond cleavage catalysis (Q33881988)

29 July 2017

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title

Importance of protein dynamics during enzymatic C-H bond cleavage catalysis (English)

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29 July 2017

Judith P Klinman

1

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29 July 2017

language of work or name

English

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publication date

12 February 2013

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29 July 2017

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29 July 2017

volume

52

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29 July 2017

issue

12

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29 July 2017

page(s)

2068-2077

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Hydrogen tunneling links protein dynamics to enzyme catalysis

29 July 2017

cites work

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5 July 2018

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Active site hydrophobic residues impact hydrogen tunneling differently in a thermophilic alcohol dehydrogenase at optimal versus nonoptimal temperatures

5 July 2018

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5 July 2018

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5 July 2018

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Investigating inner-sphere reorganization via secondary kinetic isotope effects in the C-H cleavage reaction catalyzed by soybean lipoxygenase: tunneling in the substrate backbone as well as the transferred hydrogen

5 July 2018

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5 July 2018

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5 July 2018

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Conformational relaxation following hydride transfer plays a limiting role in dihydrofolate reductase catalysis

5 July 2018

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Hydrogen-exchange mass spectrometry reveals activation-induced changes in the conformational mobility of p38alpha MAP kinase

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Intrinsic dynamics of an enzyme underlies catalysis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Hydrogen tunneling in enzyme reactions

5 July 2018

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Quantum variational transition state theory for hydrogen tunneling in enzyme catalysis

5 July 2018

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Hydrogen tunneling steps in cyclooxygenase-2 catalysis.

29 October 2018

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Biochemistry. An ensemble view of allostery.

29 October 2018

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Evidence for protein radical-mediated nuclear tunneling in fatty acid alpha-oxygenase

29 October 2018

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Hydrogen tunneling in an enzyme active site: a quantum wavepacket dynamical perspective

29 October 2018

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Oxygen isotope effects on electron transfer to O2 probed using chemically modified flavins bound to glucose oxidase

29 October 2018

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Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase.

29 October 2018

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Lipoxygenase reaction mechanism: demonstration that hydrogen abstraction from substrate precedes dioxygen binding during catalytic turnover.

29 October 2018

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Nature of Rate-Limiting Steps in the Soybean Lipoxygenase-1 Reaction

29 October 2018

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Kinetic and chemical mechanisms of yeast formate dehydrogenase.

29 October 2018

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Novel insights into cyclooxygenases, linoleate diol synthases, and lipoxygenases from deuterium kinetic isotope effects and oxidation of substrate analogs

29 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23373460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/BI301504M

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29 July 2017

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29 July 2017

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