Effects of the donor-acceptor distance and dynamics on hydride tunneling in the dihydrofolate reductase catalyzed reaction (Q28649378)

2

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Daniel Willmer

3

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Stephen J Benkovic

4

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Amnon Kohen

Journal of the American Chemical Society

5

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language of work or name

English

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publication date

25 January 2012

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published in

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volume

134

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issue

3

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page(s)

1738-45

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cites work

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Functionally important conformations of the Met20 loop in dihydrofolate reductase are populated by rapid thermal fluctuations

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Conformational change of the methionine 20 loop of Escherichia coli dihydrofolate reductase modulates pKa of the bound dihydrofolate

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Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase

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The role of enzyme dynamics and tunnelling in catalysing hydride transfer: studies of distal mutants of dihydrofolate reductase

20 June 2018

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Effects of a distal mutation on active site chemistry

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20 June 2018

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Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli

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20 June 2018

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Incorporation of hydrostatic pressure into models of hydrogen tunneling highlights a role for pressure-modulated promoting vibrations

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27 November 2018

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Tunneling and coupled motion in the Escherichia coli dihydrofolate reductase catalysis

27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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A kinetic study of wild-type and mutant dihydrofolate reductases from Lactobacillus casei

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Nature of Forces between Large Molecules of Biological Interest*

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