UCP3 translocates lipid hydroperoxide and mediates lipid hydroperoxide-dependent mitochondrial uncoupling. (Q33883328)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

UCP3 translocates lipid hydroperoxide and mediates lipid hydroperoxide-dependent mitochondrial uncoupling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

7

Elena Silvestri

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Assunta Lombardi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Rosa Anna Busiello

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Laura Napolitano

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Federica Cioffi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Maria Moreno

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Pieter de Lange

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Antonia Lanni

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

2 April 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

16599-16605

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

Uncoupling proteins: a complex journey to function discovery.

29 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

UCP2, not a physiologically relevant uncoupler but a glucose sparing switch impacting ROS production and glucose sensing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Denervation induces cytosolic phospholipase A2-mediated fatty acid hydroperoxide generation by muscle mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Stimulation of mitochondrial proton conductance by hydroxynonenal requires a high membrane potential

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Mitochondrial uncoupling proteins--what is their physiological role?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Uncoupling proteins 2 and 3 are fundamental for mitochondrial Ca2+ uniport

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

The role of uncoupling protein 3 in fatty acid metabolism: protection against lipotoxicity?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

The basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Physiological role of UCP3 may be export of fatty acids from mitochondria when fatty acid oxidation predominates: an hypothesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Low fatty acid unsaturation: a mechanism for lowered lipoperoxidative modification of tissue proteins in mammalian species with long life spans.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Energy metabolism in uncoupling protein 3 gene knockout mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

The mitochondrial permeability transition pore and its role in cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Interactions of long-chain fatty acids and albumin: determination of free fatty acid levels using the fluorescent probe ADIFAB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878051

Essential role for uncoupling protein-3 in mitochondrial adaptation to fasting but not in fatty acid oxidation or fatty acid anion export

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.102699

UCPs--unlikely calcium porters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.102699

Uncoupling protein 3 protects aconitase against inactivation in isolated skeletal muscle mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.102699

Hydroperoxy fatty acid cycling mediated by mitochondrial uncoupling protein UCP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.102699

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.102699

Determination of protein: A modification of the lowry method that gives a linear photometric response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.102699

Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.102699

A function for novel uncoupling proteins: antioxidant defense of mitochondrial matrix by translocating fatty acid peroxides from the inner to the outer membrane leaflet

21 January 2018

1 reference

12 December 2020

Expression of uncoupling protein-3 and mitochondrial activity in the transition from hypothyroid to hyperthyroid state in rat skeletal muscle

1 reference

12 December 2020

Participation of ATP/ADP antiporter in oleate- and oleate hydroperoxide-induced uncoupling suppressed by GDP and carboxyatractylate

1 reference

12 December 2020

Polyunsaturated fatty acids activate human uncoupling proteins 1 and 2 in planar lipid bilayers

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.102699

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20363757%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference