An epistatic relationship between the viral protein kinase UL97 and the UL133-UL138 latency locus during the human cytomegalovirus lytic cycle (Q33887700)

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English	An epistatic relationship between the viral protein kinase UL97 and the UL133-UL138 latency locus during the human cytomegalovirus lytic cycle	scientific article

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scholarly article

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29 July 2017

An epistatic relationship between the viral protein kinase UL97 and the UL133-UL138 latency locus during the human cytomegalovirus lytic cycle (English)

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29 July 2017

2

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10 June 2020

Christopher C Nguyen

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10 June 2020

Jeremy P. Kamil

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10 June 2020

Felicia Goodrum

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Felicia D Goodrum

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10 June 2020

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Gang Li

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10 June 2020

Mahadevaiah Umashankar

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publication date

12 March 2014

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29 July 2017

Journal of Virology

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10 June 2020

88

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10 June 2020

6047-6060

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10 June 2020

Antagonistic determinants controlling replicative and latent states of human cytomegalovirus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

5 July 2018

Biphasic euchromatin-to-heterochromatin transition on the KSHV genome following de novo infection.

1 reference

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5 July 2018

Human cytomegalovirus UL50 and UL53 recruit viral protein kinase UL97, not protein kinase C, for disruption of nuclear lamina and nuclear egress in infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

5 July 2018

Polycomb repressive complex 2 silences human cytomegalovirus transcription in quiescent infection models

1 reference

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5 July 2018

Nucleosome maps of the human cytomegalovirus genome reveal a temporal switch in chromatin organization linked to a major IE protein

1 reference

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5 July 2018

Human cytomegalovirus pUL97 regulates the viral major immediate early promoter by phosphorylation-mediated disruption of histone deacetylase 1 binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

5 July 2018

The ULb' region of the human cytomegalovirus genome confers an increased requirement for the viral protein kinase UL97.

1 reference

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5 July 2018

Inactivation of retinoblastoma protein does not overcome the requirement for human cytomegalovirus UL97 in lamina disruption and nuclear egress.

1 reference

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5 July 2018

An endothelial cell-specific requirement for the UL133-UL138 locus of human cytomegalovirus for efficient virus maturation

1 reference

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5 July 2018

An endogenous accelerator for viral gene expression confers a fitness advantage.

1 reference

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5 July 2018

Snapshots: chromatin control of viral infection

1 reference

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5 July 2018

Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a

1 reference

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5 July 2018

Histone H3 lysine 4 methylation marks postreplicative human cytomegalovirus chromatin.

1 reference

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5 July 2018

A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection

1 reference

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5 July 2018

Human cytomegalovirus-regulated paxillin in monocytes links cellular pathogenic motility to the process of viral entry

1 reference

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5 July 2018

Human cytomegalovirus early protein pUL21a promotes efficient viral DNA synthesis and the late accumulation of immediate-early transcripts

1 reference

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5 July 2018

Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1.

1 reference

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5 July 2018

Sequences of complete human cytomegalovirus genomes from infected cell cultures and clinical specimens

1 reference

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5 July 2018

Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human cytomegalovirus lacking UL97 protein kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

5 July 2018

Function of human cytomegalovirus UL97 kinase in viral infection and its inhibition by maribavir.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

5 July 2018

Characterization of a novel Golgi apparatus-localized latency determinant encoded by human cytomegalovirus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

5 July 2018

Viral mimicry of Cdc2/cyclin-dependent kinase 1 mediates disruption of nuclear lamina during human cytomegalovirus nuclear egress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

5 July 2018

Temporal dynamics of cytomegalovirus chromatin assembly in productively infected human cells

1 reference

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5 July 2018

Dynamic histone H3 acetylation and methylation at human cytomegalovirus promoters during replication in fibroblasts

1 reference

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5 July 2018

Cellular mechanisms of tumour suppression by the retinoblastoma gene.

1 reference

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5 July 2018

Phosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

5 July 2018

Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the formation of nuclear aggresomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

5 July 2018

Human cytomegalovirus: Latency and reactivation in the myeloid lineage

1 reference

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5 July 2018

Human Daxx-mediated repression of human cytomegalovirus gene expression correlates with a repressive chromatin structure around the major immediate early promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

5 July 2018

Autorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86

1 reference

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5 July 2018

Antiviral drugs for cytomegalovirus diseases

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5 July 2018

Cellular p32 recruits cytomegalovirus kinase pUL97 to redistribute the nuclear lamina

1 reference

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5 July 2018

Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141

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5 July 2018

Coding potential of laboratory and clinical strains of human cytomegalovirus

1 reference

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5 July 2018

The human cytomegalovirus UL97 protein kinase, an antiviral drug target, is required at the stage of nuclear egress

1 reference

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5 July 2018

Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action

1 reference

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5 July 2018

Effect of the human cytomegalovirus IE86 protein on expression of E2F-responsive genes: a DNA microarray analysis

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5 July 2018

Inhibition of ganciclovir-susceptible and -resistant human cytomegalovirus clinical isolates by the benzimidazole L-riboside 1263W94

1 reference

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5 July 2018

Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase

1 reference

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5 July 2018

Rb targets histone H3 methylation and HP1 to promoters

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5 July 2018

Fast screening procedures for random transposon libraries of cloned herpesvirus genomes: mutational analysis of human cytomegalovirus envelope glycoprotein genes

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5 July 2018

Murine cytomegalovirus stimulates cellular thymidylate synthase gene expression in quiescent cells and requires the enzyme for replication

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5 July 2018

The regulation of E2F by pRB-family proteins

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5 July 2018

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

1 reference

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5 July 2018

Retinoblastoma protein recruits histone deacetylase to repress transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

5 July 2018

The UL97 gene product of human cytomegalovirus is an early-late protein with a nuclear localization but is not a nucleoside kinase.

1 reference

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5 July 2018

Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains.

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5 July 2018

Induction of endogenous human cytomegalovirus gene expression after differentiation of monocytes from healthy carriers

1 reference

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Transactivation by the human cytomegalovirus IE2 86-kilodalton protein requires a domain that binds to both the TATA box-binding protein and the retinoblastoma protein.

1 reference

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5 July 2018

Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein.

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5 July 2018

The retinoblastoma gene product negatively regulates transcriptional activation mediated by the human cytomegalovirus IE2 protein

1 reference

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5 July 2018

Multiple spliced and unspliced transcripts from human cytomegalovirus immediate-early region 2 and evidence for a common initiation site within immediate-early region 1.

1 reference

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Regulated expression of early and late RNAs and proteins from the human cytomegalovirus immediate-early gene region

1 reference

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5 July 2018

Discordant expression of the immediate-early 1 and 2 gene regions of human cytomegalovirus at early times after infection involves posttranscriptional processing events.

1 reference

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5 July 2018

An inducible promoter mediates abundant expression from the immediate-early 2 gene region of human cytomegalovirus at late times after infection

1 reference

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5 July 2018

En passant mutagenesis: a two step markerless red recombination system.

1 reference

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29 October 2018

Cloning and sequencing of a highly productive, endotheliotropic virus strain derived from human cytomegalovirus TB40/E.

1 reference

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29 October 2018

Two-step red-mediated recombination for versatile high-efficiency markerless DNA manipulation in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

29 October 2018

Activated p53 suppresses the histone methyltransferase EZH2 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093856

29 October 2018

The thymidylate synthase inhibitor ZD1694 potently inhibits murine and human cytomegalovirus replication in quiescent fibroblasts.

1 reference

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29 October 2018

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10.1128/JVI.00447-14

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10 June 2020

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10 June 2020

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10 June 2020

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