Forced expression of cyclin-dependent kinase 6 confers resistance of pro-B acute lymphocytic leukemia to Gleevec treatment (Q33887799)

29 July 2017

Forced expression of cyclin-dependent kinase 6 confers resistance of pro-B acute lymphocytic leukemia to Gleevec treatment (English)

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acute lymphocytic leukemia

29 July 2017

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Tracy C Kuo

1

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29 July 2017

Joseph E Chavarria-Smith

series ordinal

2

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29 July 2017

Dan Huang

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3

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29 July 2017

Mark S Schlissel

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4

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29 July 2017

language of work or name

English

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publication date

2 May 2011

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Molecular and Cellular Biology

29 July 2017

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29 July 2017

31

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29 July 2017

2566-2576

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29 July 2017

13

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describes a project that uses

29 July 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3133375/fullTextXML

inferred from PubMed Central ID database lookup

cites work

PU.1 directly regulates cdk6 gene expression, linking the cell proliferation and differentiation programs in erythroid cells

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Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development

5 July 2018

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ERK2, but not ERK1, mediates acquired and "de novo" resistance to imatinib mesylate: implication for CML therapy

5 July 2018

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Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia

5 July 2018

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E and ID proteins branch out.

5 July 2018

1 reference

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Cell cycle, CDKs and cancer: a changing paradigm

5 July 2018

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Foxo1 directly regulates the transcription of recombination-activating genes during B cell development

5 July 2018

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Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells

5 July 2018

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Chromatin immunoprecipitation and microarray-based analysis of protein location

5 July 2018

1 reference

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Resistance to imatinib mesylate in chronic myeloid leukaemia

5 July 2018

1 reference

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Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage development

5 July 2018

1 reference

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E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells

5 July 2018

1 reference

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Beyond the cell cycle: a new role for Cdk6 in differentiation

5 July 2018

1 reference

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Helix-loop-helix proteins and lymphocyte development

5 July 2018

1 reference

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ABL oncogenes and phosphoinositide 3-kinase: mechanism of activation and downstream effectors

5 July 2018

1 reference

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p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells.

5 July 2018

1 reference

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Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts.

5 July 2018

1 reference

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The BCR-ABL story: bench to bedside and back

5 July 2018

1 reference

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p16(Ink4a) interferes with Abelson virus transformation by enhancing apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Expression of cyclin-dependent kinase 6, but not cyclin-dependent kinase 4, alters morphology of cultured mouse astrocytes

5 July 2018

1 reference

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CDK6 blocks differentiation: coupling cell proliferation to the block to differentiation in leukemic cells

5 July 2018

1 reference

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The role of PI3K in immune cells

5 July 2018

1 reference

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A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines

5 July 2018

1 reference

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Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Promotion of cell cycle progression by basic helix-loop-helix E2A

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Reprogramming leukemic cells to terminal differentiation by inhibiting specific cyclin-dependent kinases in G1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

cdk6 can shorten G(1) phase dependent upon the N-terminal INK4 interaction domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Essential roles for the Abl and Arg tyrosine kinases in neurulation

5 July 2018

1 reference

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p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Regulation of Id3 cell cycle function by Cdk-2-dependent phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Mutation of Tp53 contributes to the malignant phenotype of Abelson virus-transformed lymphoid cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Blastic transformation of p53-deficient bone marrow cells by p210bcr/abl tyrosine kinase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Abl-mediated transformation, immunoglobulin gene rearrangements and arrest of B lymphocyte differentiation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

An active v-abl protein tyrosine kinase blocks immunoglobulin light-chain gene rearrangement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

The v-abl tyrosine kinase negatively regulates NF-kappa B/Rel factors and blocks kappa gene transcription in pre-B lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

The viral and cellular forms of the Abelson (abl) oncogene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Active cdk6 complexes are predominantly nuclear and represent only a minority of the cdk6 in T cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133375

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

29 October 2018

1 reference

12 December 2020

Induction of c-myc transcription by the v-Abl tyrosine kinase requires Ras, Raf1, and cyclin-dependent kinases

1 reference

12 December 2020

Distinct factors bind to apparently homolgous sequences in the immunoglobulin heavy-chain enhancer

1 reference

12 December 2020

Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.01349-10

1 reference

29 July 2017

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29 July 2017

1 reference