A comparison of whole genome gene expression profiles of HepaRG cells and HepG2 cells to primary human hepatocytes and human liver tissues. (Q33891043)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

A comparison of whole genome gene expression profiles of HepaRG cells and HepG2 cells to primary human hepatocytes and human liver tissues (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

main subject

cell line

0 references

whole genome sequencing

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Ye Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Kaori Nakamoto

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Eva-anne Subileau

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

David Steen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Xiao-bo Zhong

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

publication date

12 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

Drug Metabolism and Disposition

19 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

988-994

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

19 January 2020

HepaRG

0 references

Hep-G2

0 references

cites work

Reproducible chemical-induced changes in gene expression profiles in human hepatoma HepaRG cells under various experimental conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Dose- and time-dependent effects of phenobarbital on gene expression profiling in human hepatoma HepaRG cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Evaluation of HepaRG cells as an in vitro model for human drug metabolism studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

HepaRG cells as an in vitro model for evaluation of cytochrome P450 induction in humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

affylmGUI: a graphical user interface for linear modeling of single channel microarray data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

The quantitative prediction of in vivo enzyme-induction caused by drug exposure from in vitro information on human hepatocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Selective suppressions of human CYP3A forms, CYP3A5 and CYP3A7, by troglitazone in HepG2 cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

CYP3A4 induction by xenobiotics: biochemistry, experimental methods and impact on drug discovery and development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

DAVID: Database for Annotation, Visualization, and Integrated Discovery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Summaries of Affymetrix GeneChip probe level data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Infection of a human hepatoma cell line by hepatitis B virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Timing of new black box warnings and withdrawals for prescription medications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Concordance of the toxicity of pharmaceuticals in humans and in animals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879958

Gene expression in human hepatocytes in suspension after isolation is similar to the liver of origin, is not affected by hepatocyte cold storage and cryopreservation, but is strongly changed after hepatocyte plating

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20228232

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Drug metabolism by the human hepatoma cell, Hep G2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20228232

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression and regulation of cytochrome P450 enzymes in primary cultures of human hepatocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20228232

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/DMD.109.031831

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20228232%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference