Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation. (Q34283856)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

review article

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title

Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation (English)

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8 November 2019

1

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8 November 2019

author name string

LeCluyse EL

series ordinal

1

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1 August 2017

language of work or name

English

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publication date

1 July 2001

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Pharmaceutical Sciences

8 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

volume

13

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8 November 2019

issue

4

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8 November 2019

page(s)

343-368

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Delayed assembly of desmosomes in keratinocytes with disrupted classic-cadherin-mediated cell adhesion by a dominant negative mutant

8 November 2019

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Effect of cell density and epidermal growth factor on the inducible expression of CYP3A and CYP1A genes in human hepatocytes in primary culture

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Evidence that cadherins play a role in the downregulation of integrin expression that occurs during keratinocyte terminal differentiation

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The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

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Two-stage glucocorticoid induction of CYP3A23 through both the glucocorticoid and pregnane X receptors

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The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

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Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

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Drug metabolism in hepatocyte sandwich cultures of rats and humans

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Changes in cellular distribution of connexins 32 and 26 during formation of gap junctions in primary cultures of rat hepatocytes

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Formation of extensive canalicular networks by rat hepatocytes cultured in collagen-sandwich configuration

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7 January 2021

Expression and regulation of cytochrome P450 enzymes in primary cultures of human hepatocytes

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Regeneration and maintenance of bile canalicular networks in collagen-sandwiched hepatocytes.

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The alcohol-inducible form of cytochrome P450 (CYP 2E1): role in toxicology and regulation of expression

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Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators

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Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

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Quantitative RT-PCR Measurement of Human Cytochrome P-450s: Application to Drug Induction Studies

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Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes

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Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions

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Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes

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Influence of extracellular matrix overlay on phenobarbital-mediated induction of CYP2B1, 2B2, and 3A1 genes in primary adult rat hepatocyte culture

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7 January 2021

10.1016/S0928-0987(01)00135-X

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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