Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts (Q33893647)

29 July 2017

title

Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts (English)

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29 July 2017

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Wasim H Chowdhury

4

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author name string

Xiaohua Ni

1

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29 July 2017

Yonggang Zhang

2

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29 July 2017

Judit Ribas

3

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29 July 2017

Mark Castanares

5

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29 July 2017

Zhewei Zhang

6

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29 July 2017

Marikki Laiho

7

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29 July 2017

Theodore L DeWeese

8

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29 July 2017

Shawn E Lupold

9

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29 July 2017

language of work or name

English

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publication date

9 May 2011

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Journal of Clinical Investigation

29 July 2017

published in

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29 July 2017

volume

121

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29 July 2017

issue

6

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29 July 2017

page(s)

2383-2390

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Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay

29 July 2017

cites work

1 reference

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Aptamer-targeted cell-specific RNA interference

5 July 2018

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Aptamers: a new class of oligonucleotides in the drug discovery pipeline?

5 July 2018

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Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors.

5 July 2018

1 reference

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Clinical radiation sensitivity with DNA repair disorders: an overview

5 July 2018

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The promises and pitfalls of RNA-interference-based therapeutics

5 July 2018

1 reference

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A three-dimensional view of the molecular machinery of RNA interference

5 July 2018

1 reference

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On the road to reading the RNA-interference code

5 July 2018

1 reference

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Chemical modification of siRNAs for in vivo use.

5 July 2018

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Cell-specific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis

5 July 2018

1 reference

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The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells

5 July 2018

1 reference

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Therapeutic application of RNAi: is mRNA targeting finally ready for prime time?

5 July 2018

1 reference

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A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose

5 July 2018

1 reference

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RNAi therapeutics: principles, prospects and challenges

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

DNA double-strand break repair: from mechanistic understanding to cancer treatment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Prostate-specific membrane antigen expression as a predictor of prostate cancer progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

siRNA targeting NBS1 or XIAP increases radiation sensitivity of human cancer cells independent of TP53 status

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Aptamer:toxin conjugates that specifically target prostate tumor cells

5 July 2018

1 reference

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Aptamer mediated siRNA delivery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Labeling tumor cells with fluorescent nanocrystal-aptamer bioconjugates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Rising prostate-specific antigen after primary prostate cancer therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Rational siRNA design for RNA interference

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Endogenous DNA double-strand breaks: Production, fidelity of repair, and induction of cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Activation of the interferon system by short-interfering RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Genome maintenance mechanisms for preventing cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Chromosomal stability and the DNA double-stranded break connection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

The DNA-dependent protein kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma: a study of 184 cases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Reaction mechanism of human DNA repair excision nuclease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Late radiation damage in prostate cancer patients treated by high dose external radiotherapy in relation to rectal dose.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

Long-term results with immediate androgen suppression and external irradiation in patients with locally advanced prostate cancer (an EORTC study): a phase III randomised trial

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104752

A Nomogram Predicting 10-Year Life Expectancy in Candidates for Radical Prostatectomy or Radiotherapy for Prostate Cancer

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21555850

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Patterns of care outcome studies: results of the national practice in adenocarcinoma of the prostate

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21555850

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI45109

1 reference

29 July 2017

1 reference

29 July 2017

1 reference