Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1. (Q33894760)

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31 January 2020

title

Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1 (English)

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31 January 2020

1

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Ying Xia

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Andy Greenfield

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author name string

Debora Bogani

2

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Pam Siggers

3

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Rachel Brixey

4

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Hilda Tateossian

5

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31 January 2020

Asha Dopplapudi

6

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Sara Wells

7

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31 January 2020

Michael Cheeseman

8

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Harry Ostrer

10

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language of work or name

English

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publication date

3 May 2011

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31 January 2020

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31 January 2020

volume

6

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issue

5

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page(s)

e19572

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Mutations in MAP3K1 cause 46,XY disorders of sex development and implicate a common signal transduction pathway in human testis determination

31 January 2020

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5 July 2018

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FGF signaling directs a center-to-pole expansion of tubulogenesis in mouse testis differentiation.

5 July 2018

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Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination

5 July 2018

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The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation

5 July 2018

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Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice

5 July 2018

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The Maestro (Mro) gene is dispensable for normal sexual development and fertility in mice

5 July 2018

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Sfrp1 and Sfrp2 are required for normal male sexual development in mice

5 July 2018

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MAP3Ks as central regulators of cell fate during development

5 July 2018

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Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

5 July 2018

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Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination

5 July 2018

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Correct dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice.

5 July 2018

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Role of mitogen-activated protein kinase kinase kinases in signal integration

5 July 2018

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Consensus statement on management of intersex disorders. International Consensus Conference on Intersex

5 July 2018

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Role of MAPKs in development and differentiation: lessons from knockout mice.

5 July 2018

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Sexually dimorphic expression of secreted frizzled-related (SFRP) genes in the developing mouse Müllerian duct

5 July 2018

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Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination

5 July 2018

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Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development.

5 July 2018

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Testis determination requires insulin receptor family function in mice

5 July 2018

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A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure

5 July 2018

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Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad

5 July 2018

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Sex determination: lessons from families and embryos

5 July 2018

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Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development.

5 July 2018

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MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

5 July 2018

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MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

5 July 2018

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Clinical review 111: familial sex reversal: a review

5 July 2018

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A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans

5 July 2018

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Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

5 July 2018

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Sertoli cells of the mouse testis originate from the coelomic epithelium.

5 July 2018

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MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis

5 July 2018

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Donor splice-site mutations in WT1 are responsible for Frasier syndrome

5 July 2018

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A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways

5 July 2018

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Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

5 July 2018

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Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death

5 July 2018

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Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9

5 July 2018

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Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

5 July 2018

1 reference

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Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

5 July 2018

1 reference

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5 July 2018

1 reference

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Familial Syndrome of Streak Gonads and Normal Male Karyotype in Five Phenotypic Females

5 July 2018

1 reference

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Genetic evidence equating SRY and the testis-determining factor

5 July 2018

1 reference

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MEK kinase 1 activity is required for definitive erythropoiesis in the mouse fetal liver.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019572

Sexually dimorphic expression of Gata-2 during mouse gonad development.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019572

Mapping a gene for 46,XY gonadal dysgenesis by linkage analysis

21 January 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019572

Sry induces cell proliferation in the mouse gonad

21 January 2018

1 reference

12 December 2020

Male-to-female sex reversal in mice lacking fibroblast growth factor 9

1 reference

12 December 2020

46,XY gonadal dysgenesis: evidence for autosomal dominant transmission in a large kindred

1 reference

12 December 2020

Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression

1 reference

12 December 2020

Loss of Fgfr2 leads to partial XY sex reversal

1 reference

12 December 2020

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0019572

Identifiers

DOI

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31 January 2020

0 references

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31 January 2020

PubMed publication ID

21559298

1 reference