Downregulation of dendritic HCN channel gating in epilepsy is mediated by altered phosphorylation signaling (Q33897319)

29 July 2017

Downregulation of dendritic HCN channel gating in epilepsy is mediated by altered phosphorylation signaling (English)

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29 July 2017

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Sangwook Jung

1

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29 July 2017

James B Bullis

2

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29 July 2017

Ignatius H Lau

3

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29 July 2017

Terrance D Jones

4

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29 July 2017

Lindsay N Warner

5

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29 July 2017

Nicholas P Poolos

6

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29 July 2017

language of work or name

English

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publication date

1 May 2010

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29 July 2017

Journal of Neuroscience

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29 July 2017

30

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29 July 2017

19

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29 July 2017

6678-6688

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2881658/fullTextXML

inferred from PubMed Central ID database lookup

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Hyperpolarization-activated cation currents in human epileptogenic neocortex

28 July 2018

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Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy

28 July 2018

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The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy

28 July 2018

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Novel mechanism for suppression of hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by receptor-like tyrosine phosphatase-alpha

28 July 2018

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Seizures beget seizures in temporal lobe epilepsies: the boomerang effects of newly formed aberrant kainatergic synapses

28 July 2018

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A cellular mechanism for dendritic spine loss in the pilocarpine model of status epilepticus.

28 July 2018

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Plasticity of intrinsic neuronal properties in CNS disorders

28 July 2018

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Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex.

28 July 2018

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Subunit-specific trafficking of GABA(A) receptors during status epilepticus

28 July 2018

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Progressive dendritic HCN channelopathy during epileptogenesis in the rat pilocarpine model of epilepsy

28 July 2018

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Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.

28 July 2018

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Constitutively active Src tyrosine kinase changes gating of HCN4 channels through direct binding to the channel proteins

28 July 2018

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Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase.

28 July 2018

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Seizure-induced plasticity of h channels in entorhinal cortical layer III pyramidal neurons

28 July 2018

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Genetic mechanisms that underlie epilepsy

28 July 2018

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Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

28 July 2018

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Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the alpha or beta catalytic subunit

28 July 2018

1 reference

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Developmental febrile seizures modulate hippocampal gene expression of hyperpolarization-activated channels in an isoform- and cell-specific manner

28 July 2018

1 reference

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Activation of JNK and p38 in rat hippocampus after kainic acid induced seizure

28 July 2018

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Effects of serine/threonine protein phosphatases on ion channels in excitable membranes

28 July 2018

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The HCN gene family: molecular basis of the hyperpolarization-activated pacemaker channels

28 July 2018

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Activity and expression of JNK1, p38 and ERK kinases, c-Jun N-terminal phosphorylation, and c-jun promoter binding in the adult rat brain following kainate-induced seizures

28 July 2018

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Dendritic hyperpolarization-activated currents modify the integrative properties of hippocampal CA1 pyramidal neurons.

28 July 2018

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Calcineurin regulation of synaptic function: from ion channels to transmitter release and gene transcription

28 July 2018

1 reference

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Modulation of ion channels by protein phosphorylation and dephosphorylation

28 July 2018

1 reference

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Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro. I. Development of seizurelike activity in low extracellular calcium.

28 July 2018

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Activity-evoked increases in extracellular potassium modulate presynaptic excitability in the CA1 region of the hippocampus

28 July 2018

1 reference

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Homeostatic regulation of synaptic excitability: tonic GABA(A) receptor currents replace I(h) in cortical pyramidal neurons of HCN1 knock-out mice

28 July 2018

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Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis

29 October 2018

1 reference

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Regulation of dendritic excitability by activity-dependent trafficking of the A-type K+ channel subunit Kv4.2 in hippocampal neurons

29 October 2018

1 reference

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Pacemaking by HCN channels requires interaction with phosphoinositides.

29 October 2018

1 reference

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Modulation of h-channels in hippocampal pyramidal neurons by p38 mitogen-activated protein kinase.

29 October 2018

1 reference

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Multiple activation mechanisms of p38alpha mitogen-activated protein kinase

29 October 2018

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Decreased IH in hippocampal area CA1 pyramidal neurons after perinatal seizure-inducing hypoxia.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

Acute p38-mediated modulation of tetrodotoxin-resistant sodium channels in mouse sensory neurons by tumor necrosis factor-alpha.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

AMPA/kainate receptor-mediated downregulation of GABAergic synaptic transmission by calcineurin after seizures in the developing rat brain.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

A behavioral role for dendritic integration: HCN1 channels constrain spatial memory and plasticity at inputs to distal dendrites of CA1 pyramidal neurons

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

Acquired dendritic channelopathy in temporal lobe epilepsy

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

Regulation of ion channel localization and phosphorylation by neuronal activity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

Tyrosine kinase inhibition differentially regulates heterologously expressed HCN channels

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

A significant increase in both basal and maximal calcineurin activity in the rat pilocarpine model of status epilepticus

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

Chronic inhibition of Ca(2+)/calmodulin kinase II activity in the pilocarpine model of epilepsy

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

A selective role of calcineurin aalpha in synaptic depotentiation in hippocampus

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

Electrophysiological mechanisms of kainic acid-induced epileptiform activity in the rat hippocampal slice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881658

The course of untreated seizures in the pilocarpine model of epilepsy

29 October 2018

1 reference

12 December 2020

Dendritic Ih normalizes temporal summation in hippocampal CA1 neurons

1 reference

12 December 2020

Calcium modulation of vascular smooth muscle ATP-sensitive K(+) channels: role of protein phosphatase-2B

1 reference

12 December 2020

HCN pacemaker channel activation is controlled by acidic lipids downstream of diacylglycerol kinase and phospholipase A2

1 reference

12 December 2020

Pacemaker current i(f) in adult canine cardiac ventricular myocytes

1 reference

12 December 2020

Contributions of the Mitogen-activated Protein (MAP) Kinase Backbone and Phosphorylation Loop to MEK Specificity

1 reference

12 December 2020

Reversible inhibition of IK, IAHP, Ih and ICa currents by internally applied gluconate in rat hippocampal pyramidal neurones

1 reference

12 December 2020

10.1523/JNEUROSCI.1290-10.2010

Identifiers

DOI

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29 July 2017

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29 July 2017

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