A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation (Q33901844)

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English	A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

retracted paper

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Retraction Watch

9 February 2024

https://doi.org/10.1158/0008-5472.CAN-23-2366

https://retractionwatch.com/?s=Samson+Jacob

https://retractionwatch.com/2022/07/25/exclusive-osu-investigation-finds-dishonesty-and-permissive-culture-of-data-manipulation-in-cancer-research-lab/

A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

3

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William A Denny

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Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Jharna Datta

1

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Europe PubMed Central

PubMed publication ID

29 July 2017

Kalpana Ghoshal

2

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Europe PubMed Central

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29 July 2017

Swarna A Gamage

4

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Europe PubMed Central

PubMed publication ID

29 July 2017

Darby G Brooke

5

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Europe PubMed Central

PubMed publication ID

29 July 2017

Pasit Phiasivongsa

6

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Europe PubMed Central

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29 July 2017

Sanjeev Redkar

7

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Europe PubMed Central

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29 July 2017

Samson T Jacob

8

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29 July 2017

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publication date

5 May 2009

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Europe PubMed Central

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29 July 2017

Cancer Research

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Europe PubMed Central

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29 July 2017

69

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Europe PubMed Central

PubMed publication ID

29 July 2017

10

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Europe PubMed Central

PubMed publication ID

29 July 2017

4277-4285

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis

1 reference

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Proteins that bind methylated DNA and human cancer: reading the wrong words

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2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1.

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DNA methylation landscapes: provocative insights from epigenomics

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Epigenetic control of tumor suppression

1 reference

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Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides

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Decitabine--bedside to bench

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Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state

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Structures of two minor-groove-binding quinolinium quaternary salts complexed with d(CGCGAATTCGCG)(2) at 1.6 and 1.8 Angstrom resolution

1 reference

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EUKARYOTIC CYTOSINE METHYLTRANSFERASES

1 reference

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5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal

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DNA methyltransferase inhibitors: old and new drugs for an epigenetic cancer therapy

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Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer

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The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites

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The history of cancer epigenetics

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10.1158/0008-5472.CAN-08-3669

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Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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