Mannose 6-phosphate/insulin-like growth factor 2 receptor, a bona fide tumor suppressor gene or just a promising candidate? (Q33904107)

29 July 2017

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title

Mannose 6-phosphate/insulin-like growth factor 2 receptor, a bona fide tumor suppressor gene or just a promising candidate? (English)

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29 July 2017

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DaCosta SA

1

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29 July 2017

Schumaker LM

series ordinal

2

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29 July 2017

Ellis MJ

series ordinal

3

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29 July 2017

publication date

1 January 2000

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Journal of Mammary Gland Biology and Neoplasia

29 July 2017

published in

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29 July 2017

volume

5

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29 July 2017

issue

1

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29 July 2017

page(s)

85-94

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Mannose-6-phosphate/insulin-like growth factor-II receptor is a receptor for retinoic acid

29 July 2017

cites work

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12 December 2020

The bovine mannose 6-phosphate/insulin-like growth factor II receptor. Localization of the insulin-like growth factor II binding site to domains 5-11.

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12 December 2020

Mannose 6-phosphate/insulin-like growth factor II receptor fails to interact with G-proteins. Analysis of mutant cytoplasmic receptor domains

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12 December 2020

Aberrant imprinting of the insulin-like growth factor II receptor gene in Wilms' tumor

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12 December 2020

Mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor. A consensus casein kinase II site followed by 2 leucines near the carboxyl terminus is important for intracellular targeting of lysosomal enzym

1 reference

12 December 2020

Microsatellite instability in in situ and invasive sporadic breast cancers of Japanese women.

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12 December 2020

The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus

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12 December 2020

Genomic structure of the human M6P/IGF2 receptor

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12 December 2020

Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors

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12 December 2020

The mannose 6-phosphate/insulin-like growth factor II receptor is a nanomolar affinity receptor for glycosylated human leukemia inhibitory factor.

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12 December 2020

Allele loss on chromosome arm 6q and fine mapping of the region at 6q27 in epithelial ovarian cancer

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12 December 2020

Subregional localization of 20 single-copy loci to chromosome 6 by fluorescence in situ hybridization

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12 December 2020

Loss of the gene encoding mannose 6-phosphate/insulin-like growth factor II receptor is an early event in liver carcinogenesis

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12 December 2020

Distinct mode of G protein activation due to single residue substitution of active IGF-II receptor peptide Arg2410-Lys2423: evidence for stimulation acceptor region other than C-terminus of Gi alpha

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12 December 2020

The structure and function of the urokinase receptor, a membrane protein governing plasminogen activation on the cell surface.

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12 December 2020

The bovine mannose 6-phosphate/insulin-like growth factor II receptor. The role of arginine residues in mannose 6-phosphate binding.

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12 December 2020

Localization of the insulin-like growth factor II (IGF-II) binding/cross-linking site of the IGF-II/mannose 6-phosphate receptor to extracellular repeats 10-11

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12 December 2020

Developmental expression of the IGF-II/mannose 6-phosphate receptor

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12 December 2020

M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity

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12 December 2020

The clinicopathological features of gastric carcinomas with microsatellite instability may be mediated by mutations of different "target genes": a study of the TGFbeta RII, IGFII R, and BAX genes

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12 December 2020

Mannose 6-phosphate/insulin-like growth factor II-binding proteins in human serum and urine. Their relation to the mannose 6-phosphate/insulin-like growth factor II receptor

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12 December 2020

Microsatellite instability and mutation of DNA mismatch repair genes in gliomas.

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12 December 2020

Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours

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12 December 2020

Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality

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12 December 2020

The insulin–like growth factor type–2 receptor gene is imprinted in the mouse but not in humans

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12 December 2020

M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-beta1

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12 December 2020

Insulin-like growth factor II (IGF-II) and the IGF-II/mannose-6-phosphate receptor: the myth continues

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12 December 2020

Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development.

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12 December 2020

Human insulin-like growth factor type I and type II receptors are not imprinted

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12 December 2020

Insulin-like growth factors I and II are produced in the metanephros and are required for growth and development in vitro

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12 December 2020

Evidence that type II insulin-like growth factor receptor is coupled to calcium gating system

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12 December 2020

Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin

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12 December 2020

Causes and consequences of microsatellite instability in endometrial carcinoma.

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12 December 2020

Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanism

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12 December 2020

Insulin-like growth factor II/cation-independent mannose 6-phosphate receptor and lysosomal enzyme recognition

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12 December 2020

Developmental regulation of the soluble form of insulin-like growth factor-II/mannose 6-phosphate receptor in human serum and amniotic fluid.

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12 December 2020

M6P/IGF2 receptor: a candidate breast tumor suppressor gene.

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12 December 2020

Interactions of pro-cathepsin D and IGF-II on the mannose-6-phosphate/IGF-II receptor

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12 December 2020

Fine-scale deletion mapping of the distal long arm of chromosome 6 in 70 human ovarian cancers

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12 December 2020

Functional Polymorphism in the Parental Imprinting of the Human IGF2R Gene

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12 December 2020

Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor

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12 December 2020

An insulin-like growth factor II (IGF-II) affinity-enhancing domain localized within extracytoplasmic repeat 13 of the IGF-II/mannose 6-phosphate receptor

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12 December 2020

The rate of internalization of the mannose 6-phosphate/insulin-like growth factor II receptor is enhanced by multivalent ligand binding

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12 December 2020

The design, expression, and characterization of human insulin-like growth factor II (IGF-II) mutants specific for either the IGF-II/cation-independent mannose 6-phosphate receptor or IGF-I receptor

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12 December 2020

Secretion of soluble insulin-like growth factor-II/mannose 6-phosphate receptor by rat tissues in culture

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12 December 2020

Mannose 6-phosphate receptors and lysosomal enzyme targeting

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12 December 2020

Intracellular traffic of the mannose 6-phosphate receptor and its ligands

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12 December 2020

Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis

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12 December 2020

The insulin-like growth factor II receptor gene is mutated in genetically unstable cancers of the endometrium, stomach, and colorectum

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12 December 2020

Local reduction of organ size in transgenic mice expressing a soluble insulin-like growth factor II/mannose-6-phosphate receptor

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12 December 2020

Comparative allelotype of in situ and invasive human breast cancer: high frequency of microsatellite instability in lobular breast carcinomas

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12 December 2020

Deletion of the M6P/IGF2r gene in primary hepatocellular carcinoma

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12 December 2020

Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene

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12 December 2020

The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-II receptor has two signals for lysosomal enzyme sorting in the Golgi

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12 December 2020

Soluble insulin-like growth factor-II/mannose 6-P receptor inhibits deoxyribonucleic acid synthesis in cultured rat hepatocytes

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12 December 2020

Early involvement of 6q in surface epithelial ovarian tumors.

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12 December 2020

Expression of the wild-type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells

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12 December 2020

Truncated forms of the insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor encompassing the IGF-II binding site: characterization of a point mutation that abolishes IGF-II binding

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12 December 2020

Disruption of ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor by cancer-associated missense mutations.

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12 December 2020

Affinity for the insulin-like growth factor-II (IGF-II) receptor inhibits autocrine IGF-II activity in MCF-7 breast cancer cells

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12 December 2020

Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction

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12 December 2020

Altered ligand binding by insulin-like growth factor II/mannose 6-phosphate receptors bearing missense mutations in human cancers

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12 December 2020

Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor gene correlates with poor differentiation in early breast carcinomas

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12 December 2020

The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R), a putative breast tumor suppressor gene

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12 December 2020

Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors

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12 December 2020

Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors

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12 December 2020

Identifiers

DOI

10.1023/A:1009571417429

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Dimensions Publication ID

29 July 2017

1027123207

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