β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D (Q33911113)

30 July 2017

title

β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D (English)

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30 July 2017

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Brian G Oliver

9

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Patrick Berger

object named as

Patrick Berger

6

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Judith Lee Black

8

object named as

Judith L Black

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30 July 2017

Thomas Trian

1

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30 July 2017

Janette K Burgess

2

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30 July 2017

Kyoko Niimi

3

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30 July 2017

Lyn M Moir

4

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30 July 2017

Qi Ge

5

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Stephen B Liggett

7

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30 July 2017

language of work or name

English

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publication date

17 May 2011

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30 July 2017

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30 July 2017

volume

6

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30 July 2017

issue

5

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30 July 2017

page(s)

e20000

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

17 May 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction

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Ca(2+) homeostasis and structural and functional remodelling of airway smooth muscle in asthma

5 July 2018

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The preclinical pharmacology of roflumilast--a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease

5 July 2018

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Airway structural components drive airway smooth muscle remodeling in asthma

5 July 2018

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Rhinovirus-induced exacerbations of asthma: How is the {beta}2-adrenoceptor implicated?

5 July 2018

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Mechanism regulating proasthmatic effects of prolonged homologous beta2-adrenergic receptor desensitization in airway smooth muscle

5 July 2018

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Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma

5 July 2018

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Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma

5 July 2018

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Crosstalk between Gi and Gq/Gs pathways in airway smooth muscle regulates bronchial contractility and relaxation

5 July 2018

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Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells

5 July 2018

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Dysfunctional interaction of C/EBPalpha and the glucocorticoid receptor in asthmatic bronchial smooth-muscle cells

5 July 2018

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PDE4D plays a critical role in the control of airway smooth muscle contraction

5 July 2018

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The phosphodiesterase inhibitor, pentoxifylline, alters rat intestinal epithelial cell proliferation via changes in the expression of transforming growth factors

5 July 2018

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Airway smooth muscle cell proliferation is increased in asthma

5 July 2018

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Prostanoids mediate IL-1beta-induced beta-adrenergic hyporesponsiveness in human airway smooth muscle cells

5 July 2018

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Beta 2-adrenoceptor agonist-mediated inhibition of human airway smooth muscle cell proliferation: importance of the duration of beta 2-adrenoceptor stimulation.

5 July 2018

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Mechanism of cytokine-induced modulation of beta-adrenoceptor responsiveness in airway smooth muscle

5 July 2018

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Terbutaline-induced desensitization of human lymphocyte beta 2-adrenoceptors. Accelerated restoration of beta-adrenoceptor responsiveness by prednisone and ketotifen

5 July 2018

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In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, beta-adrenoceptor agonists and theophylline

5 July 2018

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Steroids completely reverse albuterol-induced beta(2)-adrenergic receptor tolerance in human small airways

5 July 2018

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PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts

21 January 2018

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Roflumilast--an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial

21 January 2018

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Differences in airway remodeling between subjects with severe and moderate asthma

21 January 2018

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Phosphodiesterase 7A inhibitor ASB16165 suppresses proliferation and cytokine production of NKT cells.

21 January 2018

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Selected contribution: synergism between TNF-alpha and IL-1 beta in airway smooth muscle cells: implications for beta-adrenergic responsiveness

21 January 2018

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Effect of 1-Year Treatment with Roflumilast in Severe Chronic Obstructive Pulmonary Disease

29 October 2018

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Autonomic abnormalities and autoantibodies to beta-adrenergic receptors

21 January 2018

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12 December 2020

Autoradiographic localization of beta-adrenoceptors in asthmatic human lung

1 reference

12 December 2020

Salbutamol inhibits the proliferation of human airway smooth muscle cells grown in culture: relationship to elevated cAMP levels

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12 December 2020

Human lung cell beta 2-adrenergic receptors desensitize in response to in vivo administered beta-agonist

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Comparison of the effects of cilostazol and milrinone on intracellular cAMP levels and cellular function in platelets and cardiac cells

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Efficacy and safety of roflumilast in the treatment of asthma

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A phosphodiesterase 4 inhibitor inhibits matrix protein deposition in airways in vitro

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12 December 2020

Roflumilast, a phosphodiesterase 4 inhibitor, reduces airway hyperresponsiveness after allergen challenge

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0020000

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30 July 2017

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30 July 2017

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