Tailoring new enzyme functions by rational redesign (Q33917359)

30 July 2017

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title

Tailoring new enzyme functions by rational redesign (English)

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30 July 2017

Cedrone F

1

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PubMed ID

10981626

30 July 2017

Ménez A

series ordinal

2

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PubMed ID

10981626

30 July 2017

Quéméneur E

series ordinal

3

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30 July 2017

1 August 2000

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Current Opinion in Structural Biology

30 July 2017

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30 July 2017

10

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30 July 2017

4

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30 July 2017

405-410

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Deletion of the four C-terminal residues of PepC converts an aminopeptidase into an oligopeptidase

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Re-design of Saccharomyces cerevisiae flavocytochrome b2: introduction of L-mandelate dehydrogenase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Redesign of soluble fatty acid desaturases from plants for altered substrate specificity and double bond position

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Definition and redesign of the extended substrate specificity of granzyme B.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Probing the Kinetic Mechanism and Coenzyme Specificity of Glutathione Reductase from the CyanobacteriumAnabaenaPCC 7120 by Redesign of the Pyridine-Nucleotide-Binding Site†

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Rational design of a functional metalloenzyme: introduction of a site for manganese binding and oxidation into a heme peroxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Redesign of cytochrome c peroxidase into a manganese peroxidase: role of tryptophans in peroxidase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

The effects of an engineered cation site on the structure, activity, and EPR properties of cytochrome c peroxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Conversion of an engineered potassium-binding site into a calcium-selective site in cytochrome c peroxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Engineering the S1' subsite of trypsin: design of a protease which cleaves between dibasic residues

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Conversion of tyrosine phenol-lyase to dicarboxylic amino acid beta-lyase, an enzyme not found in nature

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Redesign of choline acetyltransferase specificity by protein engineering

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Toward tailoring the specificity of the S1 pocket of subtilisin B. lentus: chemical modification of mutant enzymes as a strategy for removing specificity limitations

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Conversion of cucumber linoleate 13-lipoxygenase to a 9-lipoxygenating species by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Conversion of mammalian 3alpha-hydroxysteroid dehydrogenase to 20alpha-hydroxysteroid dehydrogenase using loop chimeras: changing specificity from androgens to progestins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Re-design of Rhodobacter sphaeroides dimethyl sulfoxide reductase. Enhancement of adenosine N1-oxide reductase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Understanding enzyme superfamilies. Chemistry As the fundamental determinant in the evolution of new catalytic activities

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Catalytic promiscuity and the evolution of new enzymatic activities

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Engineering steroid 5 beta-reductase activity into rat liver 3 alpha-hydroxysteroid dehydrogenase.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Catalytic plasticity of fatty acid modification enzymes underlying chemical diversity of plant lipids

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Conversion of aspartate aminotransferase into an L-aspartate beta-decarboxylase by a triple active-site mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Structural basis of the conversion of T4 lysozyme into a transglycosidase by reengineering the active site

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Engineering nitrile hydratase activity into a cysteine protease by a single mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Interchange of catalytic activity within the 2-enoyl-coenzyme A hydratase/isomerase superfamily based on a common active site template

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase: synergy results in a somanase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

1 reference

7 January 2021

Microbial polyketide synthases: more and more prolific

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Dissecting and exploiting intermodular communication in polyketide synthases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Chimeric restriction enzymes: what is next?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Highly efficient endonucleolytic cleavage of RNA by a Cys(2)His(2) zinc-finger peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

A synthetic peptide ligase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Rational engineering of a miniprotein that reproduces the core of the CD4 site interacting with HIV-1 envelope glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Detection of protein three-dimensional side-chain patterns: new examples of convergent evolution.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Protein folds, functions and evolution

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https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Evolution of protein function, from a structural perspective

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https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Shotgun: getting more from sequence similarity searches

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Mapping the protein universe

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https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Analogous enzymes: independent inventions in enzyme evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Design of a novel P450: a functional bacterial-human cytochrome P450 chimera.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Combinatorial protein engineering by incremental truncation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Conversion of an antibody into an enzyme which cleaves the protein HPr

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Creation of a ribonuclease abzyme through site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Construction of new ligand binding sites in proteins of known structure

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

The construction of metal centers in proteins by rational design

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Construction of a catalytically active iron superoxide dismutase by rational protein design

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

The design of protein-based catalysts using semisynthetic methods

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Artificial metalloenzymes based on protein cavities: exploring the effect of altering the metal ligand attachment position by site directed mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Rational design of a scytalone dehydratase-like enzyme using a structurally homologous protein scaffold

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Engineering cyclophilin into a proline-specific endopeptidase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Conformational changes: how small is big enough?

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https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Directed evolution of enzyme catalysts

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https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Directed evolution of biocatalysts

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https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Protein evolution by molecular breeding

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https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

Directed evolution of new catalytic activity using the alpha/beta-barrel scaffold

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900106-8

7 January 2021

10.1016/S0959-440X(00)00106-8

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

10981626