Sigma receptors: recent advances and new clinical potentials (Q33919837)

30 July 2017

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title

Sigma receptors: recent advances and new clinical potentials (English)

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30 July 2017

Bowen WD

1

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30 July 2017

publication date

1 March 2000

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Pharmaceutica acta Helvetiae

30 July 2017

published in

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30 July 2017

volume

74

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30 July 2017

issue

2-3

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30 July 2017

page(s)

211-218

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Tardive dyskinesia with inflated neurons of the cerebellar dentate nucleus. Case reports and morphometric study

30 July 2017

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7 January 2021

(+)-6,7-Benzomorphan sigma ligands stimulate dopamine synthesis in rat corpus striatum tissue

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7 January 2021

Metabolites of haloperidol display preferential activity at sigma receptors compared to dopamine D-2 receptors

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7 January 2021

CB-64D and CB-184: ligands with high σ2 receptor affinity and subtype selectivity

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7 January 2021

Ibogaine and its congeners are sigma 2 receptor-selective ligands with moderate affinity

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7 January 2021

NE-100, a novel potent sigma ligand, preferentially binds to sigma 1 binding sites in guinea pig brain

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7 January 2021

An endogenous ligand for the sigma opioid binding site

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7 January 2021

Synthesis and evaluation of [18F] labeled benzamides: high affinity sigma receptor ligands for PET imaging.

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7 January 2021

Evidence that the potential antipsychotic agent rimcazole (BW 234U) is a specific, competitive antagonist of sigma sites in brain

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7 January 2021

Sigma receptor regulation of norepinephrine release from rat hippocampal slices

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7 January 2021

Purification, molecular cloning, and expression of the mammalian sigma1-binding site

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7 January 2021

A sigma-like binding site in rat pheochromocytoma (PC12) cells: decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different sigma receptor form from that of guinea pig brain

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7 January 2021

Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling.

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7 January 2021

Purification and characterization of the human SR 31747A-binding protein. A nuclear membrane protein related to yeast sterol isomerase

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7 January 2021

99mTc-labeled sigma-receptor-binding complex: synthesis, characterization, and specific binding to human ductal breast carcinoma (T47D) cells.

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7 January 2021

Synthesis, in vitro binding, and tissue distribution of radioiodinated 2-[125I]N-(N-benzylpiperidin-4-yl)-2-iodo benzamide, 2-[125I]BP: a potential sigma receptor marker for human prostate tumors

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7 January 2021

Enhanced kappa-opioid receptor-mediated analgesia by antisense targeting the sigma1 receptor

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7 January 2021

Reduced haloperidol in the post-mortem brains of haloperidol-treated patients

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7 January 2021

Characterization of p53 oligomerization domain mutations isolated from Li-Fraumeni and Li-Fraumeni like family members

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7 January 2021

Drug specificity of pharmacological dystonia.

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7 January 2021

Characterization of two novel sigma receptor ligands: antidystonic effects in rats suggest sigma receptor antagonism

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7 January 2021

Involvement of sigma 1 receptor in (+)-N-allylnormetazocine-stimulated hippocampal cholinergic functions in rats

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7 January 2021

Binding properties of SA4503, a novel and selective sigma 1 receptor agonist

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7 January 2021

Neuroprotective and anti-amnesic potentials of sigma (sigma) receptor ligands

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7 January 2021

Haloperidol-sensitive (+)[3H]SKF-10,047 binding sites (sigma sites) exhibit a unique distribution in rat brain subcellular fractions

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7 January 2021

Sigma-1 and sigma-2 sites in rat brain: comparison of regional, ontogenetic, and subcellular patterns

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7 January 2021

The role of calcium in the regulation of apoptosis.

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7 January 2021

Two novel sigma receptor ligands, BD1047 and LR172, attenuate cocaine-induced toxicity and locomotor activity

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7 January 2021

The mysteries of sigma receptors: new family members reveal a role in cholesterol synthesis

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7 January 2021

The effects of sigma ligands and of neuropeptide Y on N-methyl-D-aspartate-induced neuronal activation of CA3 dorsal hippocampus neurones are differentially affected by pertussin toxin

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7 January 2021

Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus

1 reference

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7 January 2021

Differentiation of sigma ligand-activated receptor subtypes that modulate NMDA-evoked [3H]-noradrenaline release in rat hippocampal slices

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7 January 2021

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7 January 2021

Calcium-dependent displacement of haloperidol-sensitive sigma receptor binding in rat hippocampal slices following tissue depolarization

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7 January 2021

Nuclear calcium transport and the role of calcium in apoptosis

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7 January 2021

Increases in rat striatal extracellular dopamine and vacuous chewing produced by two sigma receptor ligands

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7 January 2021

A proposal for the classification of sigma binding sites

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7 January 2021

JO 1784, a potent and selective ligand for rat and mouse brain sigma-sites

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7 January 2021

Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

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7 January 2021

Endogenous ligands for sigma opioid receptors in the brain ("sigmaphin"): evidence from binding assays

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7 January 2021

Steroid binding at sigma receptors suggests a link between endocrine, nervous, and immune systems

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7 January 2021

Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes

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7 January 2021

Sigma receptor-active neuroleptics are cytotoxic to C6 glioma cells in culture

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7 January 2021

Cytotoxic effects of sigma ligands: sigma receptor-mediated alterations in cellular morphology and viability.

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7 January 2021

A comparison of (-)-deoxybenzomorphans devoid of opiate activity with their dextrorotatory phenolic counterparts suggests role of sigma 2 receptors in motor function

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7 January 2021

Clinical implications of p53 mutations

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7 January 2021

1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs

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7 January 2021

Apoptosis: an overview

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7 January 2021

10.1016/S0031-6865(99)00034-5

Identifiers

DOI

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30 July 2017

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