STAT family of transcription factors in cytokine-mediated biological responses (Q33922381)

30 July 2017

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title

STAT family of transcription factors in cytokine-mediated biological responses (English)

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30 July 2017

Takeda K

1

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PubMed ID

10817963

30 July 2017

Akira S

series ordinal

2

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30 July 2017

1 September 2000

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Cytokine and Growth Factor Reviews

30 July 2017

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30 July 2017

11

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30 July 2017

3

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30 July 2017

199-207

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Cytokine signal transduction

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Signaling through the hematopoietic cytokine receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Cytokine signaling through nonreceptor protein tyrosine kinases

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

STATs: signal transducers and activators of transcription

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Distribution of the mammalian Stat gene family in mouse chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

STATs and gene regulation

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Identification of a Stat gene that functions in Drosophila development.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Anopheles gambiae Ag-STAT, a new insect member of the STAT family, is activated in response to bacterial infection

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

SH2 signaling in a lower eukaryote: a STAT protein that regulates stalk cell differentiation in dictyostelium.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Components of a Stat recognition code: evidence for two layers of molecular selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

An interleukin-4-induced transcription factor: IL-4 Stat

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Identification and localization of a skeletal muscle secrotonin 5-HT2A receptor coupled to the Jak/STAT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

A family of cytokine-inducible inhibitors of signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

A new protein containing an SH2 domain that inhibits JAK kinases

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Structure and function of a new STAT-induced STAT inhibitor

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

SOCS3 is essential in the regulation of fetal liver erythropoiesis

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Specific inhibition of Stat3 signal transduction by PIAS3

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Inhibition of Stat1-mediated gene activation by PIAS1

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Distinct tumorigenic potential of abl and raf in B cell neoplasia: abl activates the IL-6 signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Activation and association of Stat3 with Src in v-Src-transformed cell lines

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Jak-STAT signaling induced by the v-abl oncogene

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

1 reference

7 January 2021

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Functional diversity of helper T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Cytokines induce the development of functionally heterogeneous T helper cell subsets

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Essential role of Stat6 in IL-4 signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

STAT6 deficiency in a mouse model of allergen-induced airways inflammation abolishes eosinophilia but induces infiltration of CD8+ T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Stat5a is mandatory for adult mammary gland development and lactogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Defective IL-2-mediated IL-2 receptor alpha chain expression in Stat3-deficient T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900005-8

7 January 2021

10.1016/S1359-6101(00)00005-8

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

10817963