Unresponsive correlated motion in alpha7 nAChR to halothane binding explains its functional insensitivity to volatile anesthetics (Q33923082)

30 July 2017

title

Unresponsive correlated motion in alpha7 nAChR to halothane binding explains its functional insensitivity to volatile anesthetics (English)

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30 July 2017

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David Mowrey

1

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30 July 2017

Esmael J Haddadian

2

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30 July 2017

Lu Tian Liu

3

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30 July 2017

Dan Willenbring

4

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30 July 2017

Yan Xu

5

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30 July 2017

Pei Tang

6

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30 July 2017

language of work or name

English

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publication date

1 June 2010

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Journal of Physical Chemistry B

30 July 2017

published in

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30 July 2017

volume

114

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30 July 2017

issue

22

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30 July 2017

page(s)

7649-7655

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All-atom empirical potential for molecular modeling and dynamics studies of proteins

30 July 2017

cites work

1 reference

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5 July 2018

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5 July 2018

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Dynamics of firefly luciferase inhibition by general anesthetics: Gaussian and anisotropic network analyses

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Structural basis for high-affinity volatile anesthetic binding in a natural 4-helix bundle protein

5 July 2018

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Refined structure of the nicotinic acetylcholine receptor at 4A resolution

5 July 2018

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Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel.

5 July 2018

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5 July 2018

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Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

5 July 2018

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Asymmetric structural motions of the homomeric alpha7 nicotinic receptor ligand binding domain revealed by molecular dynamics simulation

5 July 2018

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Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor.

5 July 2018

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5 July 2018

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5 July 2018

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Mutation causing severe myasthenia reveals functional asymmetry of AChR signature cystine loops in agonist binding and gating.

5 July 2018

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Large-scale molecular dynamics simulations of general anesthetic effects on the ion channel in the fully hydrated membrane: the implication of molecular mechanisms of general anesthesia

5 July 2018

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5 July 2018

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Rat nicotinic ACh receptor alpha7 and beta2 subunits co-assemble to form functional heteromeric nicotinic receptor channels

5 July 2018

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5 July 2018

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Modulation of neuronal nicotinic acetylcholine receptors by halothane in rat cortical neurons

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Channel opening motion of alpha7 nicotinic acetylcholine receptor as suggested by normal mode analysis

5 July 2018

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Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors.

29 October 2018

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Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence

29 October 2018

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29 October 2018

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Identification of Nicotinic Acetylcholine Receptor Amino Acids Photolabeled by the Volatile Anesthetic Halothane

29 October 2018

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A highly conserved aspartic acid residue in the signature disulfide loop of the alpha 1 subunit is a determinant of gating in the glycine receptor

29 October 2018

1 reference

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Determinants of the anesthetic sensitivity of neuronal nicotinic acetylcholine receptors

29 October 2018

1 reference

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29 October 2018

1 reference

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Functional and molecular characterization of neuronal nicotinic ACh receptors in rat CA1 hippocampal neurons.

29 October 2018

1 reference

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Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffected

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888140

Supersensitive sites in the central nervous system. Anesthetics block brain nicotinic receptors

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888140

Large Amplitude Elastic Motions in Proteins from a Single-Parameter, Atomic Analysis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888140

Pore size and negative charge as structural determinants of permeability in the Torpedo nicotinic acetylcholine receptor channel

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20465243

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dynamics of heteropentameric nicotinic acetylcholine receptor: implications of the gating mechanism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20465243

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JP1009675

1 reference

release_w5w4cxde2vgxfovqzeatgamihm

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/w5w4cxde2vgxfovqzeatgamihm

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

2888140

1 reference

30 July 2017

1 reference