The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis. (Q33929406)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

author name string

Kwang-Pyo Lee

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Joo-Hyeon Lee

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Tae-Shin Kim

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Tack-Hoon Kim

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Hee-Dong Park

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Jin-Seok Byun

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Min-Chul Kim

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Won-Il Jeong

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Diego F Calvisi

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Jin-Man Kim

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

language of work or name

English

0 references

publication date

19 April 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

31 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

volume

107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

issue

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

page(s)

8248-8253

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

31 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

TEAD mediates YAP-dependent gene induction and growth control

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Liver stem cells: a scientific and clinical perspective.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Deletion of the Met tyrosine kinase in liver progenitor oval cells increases sensitivity to apoptosis in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

A crucial role of WW45 in developing epithelial tissues in the mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Tumor suppressor LATS1 is a negative regulator of oncogene YAP

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

YAP1 increases organ size and expands undifferentiated progenitor cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Elucidation of a universal size-control mechanism in Drosophila and mammals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Origin of hepatocellular carcinoma: role of stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Liver stem cells and their implication in hepatocellular and cholangiocarcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Liver stem cells and prospects for liver reconstitution by transplanted cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

TWEAK induces liver progenitor cell proliferation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Liver regeneration: from myth to mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Function of oval cells in hepatocellular carcinoma in rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

The origin and liver repopulating capacity of murine oval cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Mouse A6-positive hepatic oval cells also express several hematopoietic stem cell markers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

The role of hepatocytes and oval cells in liver regeneration and repopulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Generation and characterization of p53 null transformed hepatic progenitor cells: oval cells give rise to hepatocellular carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Common antigen of oval and biliary epithelial cells (A6) is a differentiation marker of epithelial and erythroid cell lineages in early development of the mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Oval cells--hepatocytes relationships in Dipin-induced hepatocarcinogenesis in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Cellular origin of cancer: dedifferentiation or stem cell maturation arrest?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Evidence for the stem cell origin of hepatocellular carcinoma and cholangiocarcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889558

Primary liver carcinoma of intermediate (hepatocyte-cholangiocyte) phenotype.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912203107

Multiple end point procedure to evaluate risk from pesticides

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912203107

Hepatic 'stem cell' malignancies in adults: four cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912203107

Dose- and time-dependent oval cell reaction in acetaminophen-induced murine liver injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912203107

The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912203107

Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912203107

Cell-specific Cre-mediated activation of the diphtheria toxin gene in pituitary tumor cells: potential for cytotoxic gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912203107

Primary liver tumour of intermediate (hepatocyte-bile duct cell) phenotype: a progenitor cell tumour?

21 January 2018

1 reference

PubMed

12 December 2020

Atypical ductular proliferation and its inhibition by transforming growth factor beta1 in the 3,5-diethoxycarbonyl-1,4-dihydrocollidine mouse model for chronic alcoholic liver disease

1 reference

PubMed

12 December 2020

1 reference

12 December 2020

Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway

1 reference

PubMed

12 December 2020

Identifiers

DOI

10.1073/PNAS.0912203107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

0 references

release_3fs32t3shnf6jkwum6tutajtbe

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3fs32t3shnf6jkwum6tutajtbe

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404163%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference