Early hepatic insulin resistance precedes the onset of diabetes in obese C57BLKS-db/db mice (Q33930211)

30 July 2017

Early hepatic insulin resistance precedes the onset of diabetes in obese C57BLKS-db/db mice (English)

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30 July 2017

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10

Aldons J Lusis

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30 July 2017

Richard C Davis

1

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30 July 2017

Lawrence W Castellani

2

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30 July 2017

Maryam Hosseini

3

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30 July 2017

Osnat Ben-Zeev

4

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30 July 2017

Hui Z Mao

5

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30 July 2017

Michael M Weinstein

6

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30 July 2017

Dae Young Jung

7

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30 July 2017

John Y Jun

8

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30 July 2017

Jason K Kim

9

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30 July 2017

Miklós Péterfy

11

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30 July 2017

language of work or name

English

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publication date

14 April 2010

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30 July 2017

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30 July 2017

59

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30 July 2017

1616-1625

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30 July 2017

7

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

30 July 2017

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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The genetic landscape of type 2 diabetes in mice

28 July 2018

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From mice to men: insights into the insulin resistance syndromes

28 July 2018

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Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

28 July 2018

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Lipin expression preceding peroxisome proliferator-activated receptor-gamma is critical for adipogenesis in vivo and in vitro.

28 July 2018

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Molecular regulation of SREBP function: the Insig-SCAP connection and isoform-specific modulation of lipid synthesis

28 July 2018

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Adipose tissue and adipokines: for better or worse

28 July 2018

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Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes

28 July 2018

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28 July 2018

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Diabetic KKAy mice exhibit increased hepatic PPARgamma1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones

28 July 2018

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Hepatic overexpression of microsomal triglyceride transfer protein (MTP) results in increased in vivo secretion of VLDL triglycerides and apolipoprotein B.

28 July 2018

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Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

28 July 2018

1 reference

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Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

28 July 2018

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Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor

28 July 2018

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Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice

28 July 2018

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Effect of genetic background on the capacity for islet cell replication in mice.

28 July 2018

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Multiple low-dose streptozotocin-induced hyperglycemia and insulitis in C57BL mice: Influence of inbred background, sex, and thymus

28 July 2018

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The influence of genetic background on the expression of the obese (ob) gene in the mouse

28 July 2018

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Genetic analysis of obesity-induced diabetes associated with a limited capacity to synthesize insulin in C57BL/KS mice: evidence for polygenic control.

28 July 2018

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Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance

28 July 2018

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Symposium IV: Diabetic syndrome in animals. Influence of genetic background on the expression of mutations at the diabetes locus in the mouse. II. Studies on background modifiers

28 July 2018

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The influence of genetic background on the susceptibility of mice to diabetes induced by alloxan and on recovery from alloxan diabetes

28 July 2018

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Chapter 4 Preparation of Isolated Rat Liver Cells

28 July 2018

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Genetic Influence of the Streptozotocin-induced Insulitis and Hyperglycemia

28 July 2018

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Dissecting the role of insulin resistance in the metabolic syndrome

28 July 2018

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Genetic analysis of the diabetes-prone C57BLKS/J mouse strain reveals genetic contribution from multiple strains

29 October 2018

1 reference

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Ultrafine mapping of SNPs from mouse strains C57BL/6J, DBA/2J, and C57BLKS/J for loci contributing to diabetes and atherosclerosis susceptibility

29 October 2018

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Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo

29 October 2018

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Both insulin signaling defects in the liver and obesity contribute to insulin resistance and cause diabetes in Irs2(-/-) mice

29 October 2018

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Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.

29 October 2018

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Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice.

29 October 2018

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Determining lipoprotein lipase and hepatic lipase activity using radiolabeled substrates.

29 October 2018

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A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

29 October 2018

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Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats.

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889760

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

29 October 2018

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12 December 2020

Alteration in expression profiles of a series of diabetes-related genes in db/db mice following treatment with thiazolidinediones

1 reference

12 December 2020

Opposite effects of background genotype on muscle and liver insulin sensitivity of lipoatrophic mice. Role of triglyceride clearance

1 reference

12 December 2020

Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility

1 reference

12 December 2020

Diabetes, a New Mutation in the Mouse

1 reference

12 December 2020

Studies in the diabetic mutant mouse. I. Light microscopy and radioautography of pancreatic islets

1 reference

12 December 2020

The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL/KsJ and C57BL/6J strains

1 reference

12 December 2020

34 Measurement of rates of lipogenesis with deuterated and tritiated water

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12 December 2020

Effects of triiodothyronine on biosynthesis and secretion of triglyceride by livers perfused in vitro with [3H]oleate and [14C]glycerol

1 reference

12 December 2020

Relationships between fatty acid synthesis and lipid secretion in the isolated perfused rat liver: effects of hyperthyroidism, glucose and oleate

1 reference

12 December 2020

Genomic analysis of the C57BL/Ks mouse strain

1 reference

12 December 2020

Comparison of five incubation systems for rat liver slices using functional and viability parameters

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12 December 2020

Identifiers

DOI

10.2337/DB09-0878

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30 July 2017

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30 July 2017

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