Ubiquitylation of Cdk9 by Skp2 facilitates optimal Tat transactivation (Q33930482)

30 July 2017

title

Ubiquitylation of Cdk9 by Skp2 facilitates optimal Tat transactivation (English)

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30 July 2017

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Matjaz Barboric

1

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30 July 2017

Fan Zhang

2

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30 July 2017

Mojca Besenicar

3

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30 July 2017

Ana Plemenitas

4

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30 July 2017

B Matija Peterlin

5

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30 July 2017

language of work or name

English

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publication date

1 September 2005

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30 July 2017

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30 July 2017

volume

79

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30 July 2017

issue

17

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30 July 2017

page(s)

11135-11141

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Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element

30 July 2017

cites work

1 reference

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Transcription-dependent degradation controls the stability of the SREBP family of transcription factors.

5 July 2018

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A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter

5 July 2018

1 reference

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CDK9 is constitutively expressed throughout the cell cycle, and its steady-state expression is independent of SKP2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

Skp2 regulates Myc protein stability and activity

5 July 2018

1 reference

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How the ubiquitin-proteasome system controls transcription

5 July 2018

1 reference

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Emerging roles of ubiquitin in transcription regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

A unified theory of gene expression

5 July 2018

1 reference

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Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome

5 July 2018

1 reference

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Ubiquitin enters the new millennium

5 July 2018

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NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

5 July 2018

1 reference

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CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

Domains in the SPT5 protein that modulate its transcriptional regulatory properties

5 July 2018

1 reference

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P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

Tat transactivation: a model for the regulation of eukaryotic transcriptional elongation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

The ability of positive transcription elongation factor B to transactivate human immunodeficiency virus transcription depends on a functional kinase domain, cyclin T1, and Tat.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 Tat function.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

Synergism between Tat and VP16 in trans-activation of HIV-1 LTR.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

VP16 and ubiquitin; binding of P-TEFb via its activation domain and ubiquitin facilitates elongation of transcription of target genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

Regulation of transcriptional activation domain function by ubiquitin

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193628

10.1128/JVI.79.17.11135-11141.2005

29 October 2018

Identifiers

DOI

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30 July 2017

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30 July 2017

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